Applications

ERC-PhD position in Catalysis

One PhD position in catalysis funded by the ERC project NIGOCAT is available in the group of Prof. Cristina Nevado at the Department of Chemistry of the University of Zürich.

Project
Our group is interested in the development of novel late transition metal catalysed reactions for the efficient construction of new C-C and C-X bonds. Lately, we have been active in the area of alkene oxidative difunctionalization, with a particular emphasis on the C-F and C-CF3 bond formation. Our goal is to develop new catalytic tools to achieve high levels of regio- and stereocontrol in these novel processes.

Responsibilities and Conditions

Primary responsibilities will involve the rational design and implementation of novel protocols in the area of homogeneous catalysis. Synthetic studies will be supported by computationally as well as experimentally driven mechanistic studies (reaction kinetics, deuterium labelling studies, isolation of organometallic intermediates, etc…).

Eligibility Criteria
Candidates must hold Bachelor/Master in Organic Chemistry at the time of submission of applications.
The ideal candidate for this position should have a solid knowledge and practical experience in organic chemistry and be familiar with techniques such as inert atmosphere, NMR, UV-Vis, IR, MS, etc…Previous experience in the area of computational or physical organic chemistry will be a plus. Good command in English, both oral and written is also required. We are looking for creative, determined and ambitious students eager to explore projects at the interface of Catalysis and Synthesis.

Duration of the contract: 3 (+1) years. Starting date: 1st quarter 2017.

Applications
Applications of strongly motivated candidates containing a cover letter, research summary of past accomplishments, CV (resumé), and 1 letter of support (or the names and contact details of 2 referees) should be sent to:
nevado.group@gmail.com
Prof. Cristina Nevado
Department of Chemistry-University of Zürich
Winterthurerstrasse 190, CH-8057. Zürich (Switzerland)
(Incomplete applications will NOT be considered)

 


 

PhD position in Organic Synthesis/Medicinal Chemistry

One PhD position in Organic Synthesis/Medicinal Chemistry funded by the SNSF is available in the group of Prof. Cristina Nevado at the Department of Chemistry of the University of Zürich.

Project
Our group is interested in the study, at a molecular level, of relevant biological processes such as cancer progression, cancer metastasis and cell motility. We design, synthesize and use organic molecules as probes to better understand these highly complex but fundamental problems. Recently, bromodomain proteins, epigenetic readers, have emerged as relevant targets for drug discovery due, in a large extent, to their involvement in the regulation of multiple genes. Rooted in chemical synthesis, our goal is to provide new chemical tools to study these fascinating proteins and their biological role.

Responsibilities and Conditions

Primary responsibilities will involve the rational design and synthesis of novel, complex molecular scaffolds and the evaluation of their biological activity in diverse in vitro/in vivo models.

Duration of the contract: 3 (+1) years. Starting date: 1st quarter 2017.

Eligibility Criteria
Candidates must hold Bachelor/Master in Organic Chemistry at the time of submission of applications.
The ideal candidate for this position should have a solid knowledge and practical experience in organic chemistry and be familiar with techniques such as NMR, UV-Vis, IR, MS, etc…Previous experience in the area of chemical biology will be a plus. Good command in English, both oral and written is also required. We are looking for innovative, determined and ambitious students eager to explore projects at the interface of Chemistry and Biology.

Applications
Applications of strongly motivated candidates containing a cover letter, research summary of past accomplishments, CV (resumé), and 1 letter of support (or the names and contact details of 2 referees) should be sent per email to:
nevado.group@gmail.com
Prof. Cristina Nevado
Department of Chemistry-University of Zürich
Winterthurerstrasse 190, CH-8057. Zürich (Switzerland)
(Incomplete applications will NOT be considered)