Organic synthesis lies at the core of every advanced technology in our modern world: first, providing substances for further development and usage for other disciplines but also delivering previously unprecedented scaffolds. As the construction of complex molecular architectures from chemical building blocks still remains a far-from-routine task, the discovery of methodologies to increase the control over reactivity, while achieving molecular complexity with high levels of efficiency, is still one of the frontier challenges of chemistry in the 21st century.
Our group aims to develop a multidisciplinary research program supported on three pillars: first, the development of new processes for the construction of C-C and C-X bonds based on late-transition metal catalysis; second, the implementation of such methods to streamline the synthesis of complex natural products. A third focus is the study at a molecular level, both computational and experimentally, of relevant biological processes influenced by these advanced organic molecules such as cancer progression, cancer metastasis and cell motility. Our main contributions to each of these fields are summarized below.