Metalorganic and Organocatalytic Methods for Enantioselective C-C bond Formations

The lecture covers recent advances for enantioselective Henry- and aldol-reactions. The synthesis and structures of new Cu(II) complexes is reported which catalyze the Henry reaction with ee values up to 99%. Aldol reactions will be presented using new proline derivatives – in this context a very short route to a-tocopherol (93% ee) has been developed.