Researchers involved in the project

Prof. Dr. Cristina Nevado Department of Chemistry, University of Zurich
	The main interest of the group is to synthesize selective bromodomain ligands and smart chemical probes to modulate and interrogate bromodomain activity.
*Associated researchers*
Eleen Laul	Leonardo Palaferri	Dr. Katherine Rollins	Dr. Iván Cheng Sánchez

Prof. Dr. Amedeo Caflisch Department of Biochemistry, University of Zurich
	The fundamental motivation for our research is understanding how life works, in particular in the context of human disease. The biochemists test and refine the structural properties of suitable inhibitors and their ability to block bromodomains on the computer and in the test tube
*Associated researchers*
Ilaria Salutari	Dr. Lars Wiedmer	Dr. Xiang Wang

Prof. Dr. Christian Mosimann School of Medicine Department of Pediatrics, Section of Developmental Biology, University of Colorado Denver
	The aim of our lab's research is to understand how cells acquire their fates during development and how these processes go wrong in congenital disease. We investigate suitable lead substances to find out their effects on the blood-forming system of zebra fish, an important research model where each type of cell can be marked as desired and tracked microscopically from outside.
*Associated researchers*
Dr. Alexa Burger	Susan Nieuwenhuize

Prof. Dr. Tuncay Baubec Department of Molecular Mechanisms of Disease, University of Zurich
	Multicellular organisms have evolved sophisticated networks to regulate gene expression through chemical modifications on chromatin. This layer of epigenetic regulation has to be precisely controlled and interpreted in order to orchestrate correct execution of gene expression programs. Our group aims to understand how regulatory proteins containing bromodomains bind to the genome based on histone acetylation. Towards this we combine genome engineering with functional genomics and computational biology approaches in mouse stem cells.
*Associated researchers*
Dr. Ino Karemaker	Davide Recchia	Dr. Nina Alexandra Schmolka