Publications

ZORA Publication List

Publications

• 2026

  • Journal Article

    • Lei, F., Bigler, L., Weckerle, C., & Saldanha, L. L. (2026). Discovery of chemical markers for maidong (roots of Ophiopogon japonicus and Liriope spicata): A feature-based molecular networking approach Journal of Pharmaceutical and Biomedical Analysis, 267, 117158. https://doi.org/10.1016/j.jpba.2025.117158

• 2025

  • Journal Article

    • Golaz, D., Bürgi, L., Egli, M., Bigler, L., & Pessi, G. (2025). The Siderophore Phymabactin Facilitates the Growth of the Legume Symbiont Paraburkholderia phymatum in Aluminium-Rich Martian Soil Life, 15, 1044. https://doi.org/10.3390/life15071044
    • Mendoz Diaz, O., Tell, A., Hangartner, S., Hutter, J., Stalder, U., Friedl, H., Buser, A. M., Kern, S., Bigler, L., Bleiner, D., & Heeb, N. V. (2025). Determination of chlorinated paraffins and olefins in plastic consumer products of the Swiss market Chemosphere, 374, 144239. https://doi.org/10.1016/j.chemosphere.2025.144239
    • Hutter, J., Mendo Diaz, O., Knobloch, M., Zennegg, M., Vogel, J. C., Durisch, E., Stalder, U., Bigler, L., Kern, S., Buser, A. M., & Heeb, N. V. (2025). Temporal trends and spatial variations of chlorinated paraffins and olefins in sewage sludge from eight Swiss wastewater treatment plants from 1993 to 2020 Chemosphere, 372, 144071. https://doi.org/10.1016/j.chemosphere.2025.144071
    • Mathis, F., Iten, S., Knobloch, M., Fleischmann, T., Stalder, U., Bleiner, D., Kern, S., Bigler, L., Kohler, H.-P. E., & Heeb, N. V. (2025). The metabolome of Sphingobium chinhatense IP26 exposed to chlorinated paraffins – Efficient data analysis with RASER Chemosphere, 373, 144160. https://doi.org/10.1016/j.chemosphere.2025.144160
    • Guérin, A., Levasseur, C., Herger, A., Renggli, D., Sotiropoulos, A. G., Kadler, G., Hou, X., Schaufelberger, M., Meyer, C., Wicker, T., Bigler, L., & Ringli, C. (2025). Histidine limitation alters plant development and influences the TOR network Journal of Experimental Botany, 76, 1085–1098. https://doi.org/10.1093/jxb/erae479

• 2024

  • Journal Article

    • Vollenweider, V., Rehm, K., Chepkirui, C., Pérez-Berlanga, M., Polymenidou, M., Piel, J., Bigler, L., & Kümmerli, R. (2024). Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens ELife, 13, RP92493. https://doi.org/10.7554/eLife.92493.3
    • Lang, J., Ramos, S. E., Reichert, L., Amboka, G. M., Apel, C., Chidawanyika, F., Detebo, A., Librán-Embid, F., Meinhof, D., Bigler, L., & Schuman, M. C. (2024). Push–Pull Intercropping Increases the Antiherbivore Benzoxazinoid Glycoside Content in Maize Leaf Tissue ACS Agricultural Science & Technology, 4, 1074–1082. https://doi.org/10.1021/acsagscitech.4c00386
    • Jeong, S., Schütz, V., Demir, F., Preusche, M., Huesgen, P., Bigler, L., Kovacic, F., Gutbrod, K., Dörmann, P., & Schulz, M. (2024). Cyclic Isothiocyanate Goitrin Impairs Lotus japonicus Nodulation, Affects the Proteomes of Nodules and Free Mesorhizobium loti, and Induces the Formation of Caffeic Acid Derivatives in Bacterial Cultures Plants, 13, 2897. https://doi.org/10.3390/plants13202897
    • Gu, S., Shao, Y., Rehm, K., Bigler, L., Zhang, D., He, R., Xu, R., Shao, J., Jousset, A., Friman, V.-P., Bian, X., Wei, Z., Kümmerli, R., & Li, Z. (2024). Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways ELife, 13, RP96719. https://doi.org/10.7554/elife.96719.3
    • Mendo Diaz, O., Patiny, L., Tell, A., Hutter, J., Knobloch, M., Stalder, U., Kern, S., Bigler, L., Heeb, N., & Bleiner, D. (2024). A Quasi Real-Time Evaluation of High-Resolution Mass Spectra of Complex Chlorinated Paraffin Mixtures and Their Transformation Products Analytical Chemistry, 96, 12378–12386. https://doi.org/10.1021/acs.analchem.4c01723
    • Schiefelbein, K., Lang, J., Schuster, M., Grigglestone, C. E., Striga, R., Bigler, L., Schuman, M. C., Zerbe, O., Li, Y., & Hartrampf, N. (2024). Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides Journal of the American Chemical Society, 146, 17261–17269. https://doi.org/10.1021/jacs.4c03898
    • Gu, S., Shao, Y., Rehm, K., Bigler, L., Zhang, D., He, R., Xu, R., Shao, J., Jousset, A., Friman, V.-P., Bian, X., Wei, Z., Kümmerli, R., & Li, Z. (2024). From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways ELife, 13, RP96719. https://doi.org/10.7554/elife.96719.1
    • Lang, J., Ramos, S. E., Smohunova, M., Bigler, L., & Schuman, M. C. (2024). Screening of leaf extraction and storage conditions for eco‐metabolomics studies Plant Direct, 8, e578. https://doi.org/10.1002/pld3.578
    • Knobloch, M. C., Hutter, J., Diaz, O. M., Zennegg, M., Vogel, J. C., Durisch, E., Stalder, U., Bigler, L., Kern, S., Bleiner, D., & Heeb, N. V. (2024). Evolution of chlorinated paraffin and olefin fingerprints in sewage sludge from 1993 to 2020 of a Swiss municipal wastewater treatment plant Chemosphere, 349, 140825. https://doi.org/10.1016/j.chemosphere.2023.140825
    • Rehm, K., Hankele, A.-K., Ulbrich, S. E., & Bigler, L. (2024). Quantification of glucocorticoid and progestogen metabolites in bovine plasma, skimmed milk and saliva by UHPLC-HR-MS with polarity switching Analytica Chimica Acta, 1287, 342118. https://doi.org/10.1016/j.aca.2023.342118

• 2023

  • Journal Article

    • Mendo Diaz, O., Tell, A., Knobloch, M., Canonica, E., Walder, C., Buser, A. M., Stalder, U., Bigler, L., Kern, S., Bleiner, D., & Heeb, N. V. (2023). Fingerprinting of chlorinated paraffins and their transformation products in plastic consumer products Chemosphere, 338, 139552. https://doi.org/10.1016/j.chemosphere.2023.139552
    • Hofmann, D., Thiele, B., Siebers, M., Rahmati, M., Schütz, V., Jeong, S., Cui, J., Bigler, L., Held, F., Wu, B., Babic, N., Kovacic, F., Hamacher, J., Hölzl, G., Dörmann, P., & Schulz, M. (2023). Implications of Below-Ground Allelopathic Interactions of Camelina sativa and Microorganisms for Phosphate Availability and Habitat Maintenance Plants, 12, 2815. https://doi.org/10.3390/plants12152815
    • Rehm, K., Vollenweider, V., Kümmerli, R., & Bigler, L. (2023). Pyoverdine Analysis – From High-resolution MS/MS Fragmentation to Ion Mobility Measurements Chimia, 77, 250. https://doi.org/10.2533/chimia.2023.250
    • Rehm, K., Vollenweider, V., Gu, S., Friman, V.-P., Kümmerli, R., Wei, Z., & Bigler, L. (2023). Chryseochelins—structural characterization of novel citrate-based siderophores produced by plant protecting Chryseobacterium spp Metallomics, 15, mfad008. https://doi.org/10.1093/mtomcs/mfad008
    • Rehm, K., Vollenweider, V., Kümmerli, R., & Bigler, L. (2023). Rapid identification of pyoverdines of fluorescent Pseudomonas spp. by UHPLC-IM-MS Biometals, 36, 19–34. https://doi.org/10.1007/s10534-022-00454-w

  • Master's Thesis

    • Bigler, L. (2023). Thawing permafrost - Sedimentary organic matter distribution across the Canadian Beaufort Sea (Master’s thesis, University of Zurich) https://doi.org/10.5167/uzh-252801

• 2022

  • Journal Article

    • Knobloch, M. C., Mathis, F., Diaz, O. M., Stalder, U., Bigler, L., Kern, S., Bleiner, D., & Heeb, N. V. (2022). Selective and Fast Analysis of Chlorinated Paraffins in the Presence of Chlorinated Mono-, Di-, and Tri-Olefins with the R-Based Automated Spectra Evaluation Routine (RASER) Analytical Chemistry, 94, 13777–13784. https://doi.org/10.1021/acs.analchem.2c02240
    • Girel, S., Schütz, V., Bigler, L., Dörmann, P., & Schulz, M. (2022). Bioactive Nitrosylated and Nitrated N-(2-hydroxyphenyl)acetamides and Derived Oligomers: An Alternative Pathway to 2-Amidophenol-Derived Phytotoxic Metabolites Molecules, 27, 4786. https://doi.org/10.3390/molecules27154786
    • Rehm, K., Vollenweider, V., Kümmerli, R., & Bigler, L. (2022). A comprehensive method to elucidate pyoverdines produced by fluorescent Pseudomonas spp. by UHPLC-HR-MS/MS Analytical and Bioanalytical Chemistry, 414, 2671–2685. https://doi.org/10.1007/s00216-022-03907-w

• 2021

  • Journal Article

    • Guan, P., Zhou, J., Girel, S., Zhu, X., Schwab, M., Zhang, K., Wang‐Müller, Q., Bigler, L., & Nick, P. (2021). Anti‐microtubule activity of the traditional Chinese medicine herb Northern Ban Lan ( Isatis tinctoria ) leads to glucobrassicin Journal of Integrative Plant Biology, 63, 2058–2074. https://doi.org/10.1111/jipb.13177
    • Sieber, S., Mathew, A., Jenul, C., Kohler, T., Bär, M., Carrión, V. J., Cazorla, F. M., Stalder, U., Hsieh, Y.-C., Bigler, L., Eberl, L., & Gademann, K. (2021). Mitigation of Pseudomonas syringae virulence by signal inactivation Science Advances, 7, eabg2293. https://doi.org/10.1126/sciadv.abg2293
    • Payandeh, S., Rentsch, D., Łodziana, Z., Asakura, R., Bigler, L., Černý, R., Battaglia, C., & Remhof, A. (2021). Nido‐Hydroborate‐Based Electrolytes for All‐Solid‐State Lithium Batteries Advanced Functional Materials, 31, 2010046. https://doi.org/10.1002/adfm.202010046
    • Schumacher, I., Ndinyanka Fabrice, T., Abdou, M.-T., Kuhn, B. M., Voxeur, A., Herger, A., Roffler, S., Bigler, L., Wicker, T., & Ringli, C. (2021). Defects in Cell Wall Differentiation of the Arabidopsis Mutant rol1-2 Is Dependent on Cyclin-Dependent Kinase CDK8 Cells, 10, 685. https://doi.org/10.3390/cells10030685
    • Rehm, K., Hankele, A. K., Ulbrich, S. E., & Bigler, L. (2021). Simultaneous quantification of progestogens in plasma and serum by UHPLC-HRMS employing multiplexed targeted single ion monitoring Talanta, 232, 122358. https://doi.org/10.1016/j.talanta.2021.122358

• 2020

  • Journal Article

    • Ozdas, M. S., Shah, A. S., Johnson, P. M., Patel, N., Marks, M., Yasar, T. B., Stalder, U., Bigler, L., von der Behrens, W., Sirsi, S. R., & Yanik, M. F. (2020). Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers Nature Communications, 11, 4929. https://doi.org/10.1038/s41467-020-18059-7
    • Forster, Y. M., Reusser, S., Forster, F., Bienz, S., & Bigler, L. (2020). VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms Metabolites, 10, 327. https://doi.org/10.3390/metabo10080327
    • Forster, Y. M., Green, J. L., Khatiwada, A., Liberato, J. L., Narayana Reddy, P. A., Salvino, J. M., Bienz, S., Bigler, L., dos Santos, W. F., & Karklin Fontana, A. C. (2020). Elucidation of the Structure and Synthesis of Neuroprotective Low Molecular Mass Components of the Parawixia bistriata Spider Venom ACS Chemical Neuroscience, 11, 1573–1596. https://doi.org/10.1021/acschemneuro.0c00007
    • Woodhams, D. C., Rollins-Smith, L. A., Reinert, L. K., Lam, B. A., Harris, R. N., Briggs, C. J., Vredenburg, V. T., Patel, B. T., Caprioli, R. M., Chaurand, P., Hunziker, P., & Bigler, L. (2020). Probiotics Modulate a Novel Amphibian Skin Defense Peptide That Is Antifungal and Facilitates Growth of Antifungal Bacteria Microbial Ecology, 79, 192–202. https://doi.org/10.1007/s00248-019-01385-9
    • Hankele, A. K., Rehm, K., Berard, J., Schuler, G., Bigler, L., & Ulbrich, S. E. (2020). Progestogen profiling in plasma during the estrous cycle in cattle using an LC-MS based approach Theriogenology, 142, 376–383. https://doi.org/10.1016/j.theriogenology.2019.10.005

• 2019

  • Journal Article

    • Van der Weijden, V. A., Hankele, A.-K., Rüegg, A. B., Schmicke, M., Rehm, K., Bigler, L., & Ulbrich, S. E. (2019). Progestogen Profiling Over the Course of Diapause and Resumption of Embryo Development in the European Roe Deer SciMedicine Journal, 1, 158–167. https://doi.org/10.28991/scimedj-2019-0104-1
    • Schütz, V., Bigler, L., Girel, S., Laschke, L., Sicker, D., & Schulz, M. (2019). Conversions of Benzoxazinoids and Downstream Metabolites by Soil Microorganisms Frontiers in Ecology and Evolution, 7:238. https://doi.org/10.3389/fevo.2019.00238
    • Hahn, M. A., Effertz, C., Bigler, L., & von Elert, E. (2019). 5α-cyprinol sulfate, a bile salt from fish, induces diel vertical migration in Daphnia ELife, 8, e44791. https://doi.org/10.7554/elife.44791
    • Borjas Nevarez, R., Kim, E., Childs, B. C., Braband, H., Bigler, L., Stalder, U., Alberto, R., Weck, P. F., & Poineau, F. (2019). Zirconium chloride molecular species: combining electron impact mass spectrometry and first principles calculations SN Applied Sciences, 1, 392. https://doi.org/10.1007/s42452-019-0410-y

• 2018

  • Journal Article

    • Hahn, M., von Elert, E., Bigler, L., Díaz Hernández, M. D., & Schloerer, N. E. (2018). 5α-Cyprinol sulfate: Complete NMR assignment and revision of earlier published data, including the submission of a computer-readable assignment in NMReDATA format Magnetic Resonance in Chemistry (MRC), 56, 1201–1207. https://doi.org/10.1002/mrc.4782
    • Childs, B. C., Lawler, K. V., Braband, H., Mast, D. S., Bigler, L., Stalder, U., Peterson, D. R., Jansen, A., Forster, P. M., Czerwinski, K. R., Alberto, R., Sattelberger, A. P., & Poineau, F. (2018). The Nature of the Technetium Species Formed During the Oxidation of Technetium Dioxide with Oxygen and Water European Journal of Inorganic Chemistry, 2018, 1137–1144. https://doi.org/10.1002/ejic.201701199

• 2017

  • Journal Article

    • Niewoehner, O., Garcia-Doval, C., Rostøl, J. T., Berk, C., Schwede, F., Bigler, L., Hall, J., Marraffini, L. A., & Jinek, M. (2017). Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers Nature, 548, 543–548. https://doi.org/10.1038/nature23467
    • Bucher, R., Veyel, D., Willmitzer, L., Krattinger, S. G., Keller, B., & Bigler, L. (2017). Combined GC- and UHPLC-HR-MS based metabolomics to analyze durable anti-fungal resistance processes in cereals Chimia, 71, 156–159. https://doi.org/10.2533/chimia.2017.156
    • Kuhn, B. M., Nodzyński, T., Errafi, S., Bucher, R., Gupta, S., Aryal, B., Dobrev, P., Bigler, L., Geisler, M., Zažímalová, E., Friml, J., & Ringli, C. (2017). Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity Scientific Reports, 7, 41906. https://doi.org/10.1038/srep41906
    • Davis, L. R., Bigler, L., & Woodhams, D. C. (2017). Developmental trajectories of amphibian microbiota: response to bacterial therapy depends on initial community structure Environmental Microbiology, 19, 1502–1517. https://doi.org/10.1111/1462-2920.13707

• 2016

  • Journal Article

    • Childs, B. C., Braband, H., Lawler, K., Mast, D. S., Bigler, L., Stalder, U., Forster, P. M., Czerwinski, K. R., Alberto, R., Sattelberger, A. P., & Poineau, F. (2016). Ditechnetium heptoxide revisited: solid-state, gas-phase, and theoretical studies Inorganic Chemistry, 55, 10445–10452. https://doi.org/10.1021/acs.inorgchem.6b01683
    • Kuhn, B. M., Errafi, S., Bucher, R., Dobrev, P., Geisler, M., Bigler, L., Zažímalová, E., & Ringli, C. (2016). 7-Rhamnosylated flavonols modulate homeostasis of the plant hormone auxin and affect plant development Journal of Biological Chemistry, 291, 5385–5395. https://doi.org/10.1074/jbc.M115.701565
    • Sasse, J., Schlegel, M., Borghi, L., Ullrich, F., Lee, M., Liu, G.-W., Giner, J.-L., Kayser, O., Bigler, L., Martinoia, E., & Kretzschmar, T. (2016). Petunia hybrida PDR2 is involved in herbivore defense by controlling steroidal contents in trichomes Plant, Cell & Environment, 39, 2725–2739. https://doi.org/10.1111/pce.12828
    • Pavlovic, I., Thakor, D. T., Vargas, J. R., McKinlay, C. J., Hauke, S., Anstaett, P., Camuña, R. C., Bigler, L., Gasser, G., Schultz, C., Wender, P. A., & Jessen, H. J. (2016). Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo Nature Communications, 7, 10622. https://doi.org/10.1038/ncomms10622
    • Ruiz-Sola, M. Á., Coman, D., Beck, G., Barja, M. V., Colinas, M., Graf, A., Welsch, R., Rütimann, P., Bühlmann, P., Bigler, L., Gruissem, W., Rodríguez-Concepción, M., & Vranová, E. (2016). Arabidopsis GERANYLGERANYL DIPHOSPHATE SYNTHASE 11 is a hub isozyme required for the production of most photosynthesis-related isoprenoids New Phytologist, 209, 252–264. https://doi.org/10.1111/nph.13580
    • Saner, P., Philipson, C. D., Peters, S., Keller, F., Bigler, L., Turnbull, L. A., & Hector, A. (2016). Growth rates and relative change in non-structural carbohydrates of dipterocarp seedlings in response to light acclimation Plant Ecology and Diversity, 9, 491–504. https://doi.org/10.1080/17550874.2016.1227385
    • Woodhams, D. C., Bell, S. C., Bigler, L., Caprioli, R. M., Chaurand, P., Lam, B. A., Reinert, L. K., Stalder, U., Vazquez, V. M., Schliep, K., Hertz, A., & Rollins-Smith, L. A. (2016). Life history linked to immune investment in developing amphibians Conservation Physiology, 4, cow025. https://doi.org/10.1093/conphys/cow025

  • Edited Scientific Work

    • Bienz, S., Bigler, L., Fox, T., & Meier, H. (Eds.). (2016). Spektroskopische Methoden in der organischen Chemie Georg Thieme Verlag.

• 2015

  • Journal Article

    • Pavlovic, I., Thakor, D. T., Bigler, L., Wilson, M. S. C., Laha, D., Schaaf, G., Saiardi, A., & Jessen, H. J. (2015). Prometabolites of 5-Diphospho-myo-inositol Pentakisphosphate Angewandte Chemie Internationale Edition, 54, 9622–9626. https://doi.org/10.1002/anie.201503094
    • Salata, C., Baritussio, A., Munegato, D., Calistri, A., Ha, H. R., Bigler, L., Fabris, F., Parolin, C., Palu, G., & Mirazimi, A. (2015). Amiodarone and metabolite MDEA inhibit Ebola virus infection by interfering with the viral entry process FEMS Pathogens and Disease, 73, ftv032–ftv032. https://doi.org/10.1093/femspd/ftv032
    • Semmler, A., Heese, P., Stoffel-Wagner, B., Muschler, M., Heberlein, A., Bigler, L., Prost, J. C., Frieling, H., Kornhuber, J., Banger, M., Bleich, S., Hillemacher, T., & Linnebank, M. (2015). Alcohol abuse and cigarette smoking are associated with global DNA hypermethylation: results from the German Investigation on Neurobiology in Alcoholism (GINA) Alcohol, 49, 97–101. https://doi.org/10.1016/j.alcohol.2015.01.004
    • Chauhan, H., Boni, R., Bucher, R., Kuhn, B., Buchmann, G., Sucher, J., Selter, L. L., Hensel, G., Kumlehn, J., Bigler, L., Glauser, G., Wicker, T., Krattinger, S. G., & Keller, B. (2015). The wheat resistance gene Lr34 results in the constitutive induction of multiple defense pathways in transgenic barley The Plant Journal, 84, 202–215. https://doi.org/10.1111/tpj.13001

• 2014

  • Journal Article

    • Artus, G. R. J., Bigler, L., & Seeger, S. (2014). Superficial dopants allow growth of silicone nanofilaments on hydroxyl-free substrates Langmuir, 30, 10308–10316. https://doi.org/10.1021/la501991e
    • Dudnik, A., Bigler, L., & Dudler, R. (2014). Production of Proteasome Inhibitor Syringolin A by the Endophyte Rhizobium sp Strain AP16 Applied and Environmental Microbiology, 80, 3741–3748. https://doi.org/10.1128/AEM.00395-14
    • Küng, D., Bigler, L., Davis, L. R., Gratwicke, B., Griffith, E., & Woodhams, D. C. (2014). Stability Of microbiota facilitated by host immune regulation: Informing probiotic strategies to manage amphibian disease PLoS ONE, 9, e87101. https://doi.org/10.1371/journal.pone.0087101
    • Schiestl, F. P., Kirk, H., Bigler, L., Cozzolino, S., & Desurmont, G. A. (2014). Herbivory and floral signaling: phenotypic plasticity and tradeoffs between reproduction and indirect defense New Phytologist, 203, 257–266. https://doi.org/10.1111/nph.12783

• 2013

  • Journal Article

    • Tzouros, M., Chesnov, S., Bigler, L., & Bienz, S. (2013). A template approach for the characterization of linear polyamines and derivatives in spider venom European Journal of Mass Spectrometry, 19, 57–69. https://doi.org/10.1255/ejms.1213
    • Semmler, A., Prost, J. C., Smulders, Y., Smith, D., Blom, H., Bigler, L., & Linnebank, M. (2013). Methylation metabolism in sepsis and systemic inflammatory response syndrome Scandinavian Journal of Clinical and Laboratory Investigation, 73, 368–372. https://doi.org/10.3109/00365513.2013.785587
    • Dudnik, A., Bigler, L., & Dudler, R. (2013). Heterologous expression of a Photorhabdus luminescens syrbactin-like gene cluster results in production of the potent proteasome inhibitor glidobactin A Microbiological Research, 168, 73–76. https://doi.org/10.1016/j.micres.2012.09.006

• 2012

  • Journal Article

    • Woodhams, D. C., Bigler, L., & Marschang, R. (2012). Tolerance of fungal infection in European water frogs exposed to Batrachochytrium dendrobatidis after experimental reduction of innate immune defenses BMC Veterinary Research, 8, 197. https://doi.org/10.1186/1746-6148-8-197
    • Storari, M., Bigler, L., Gessler, C., & Broggini, G. A. L. (2012). Assessment of the ochratoxin A production ability of Aspergillus tubingensis Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment, 29, 1450–1454. https://doi.org/10.1080/19440049.2012.698656
    • Storari, M., Dennert, F. G., Bigler, L., Gessler, C., & Broggini, G. A. L. (2012). Isolation of mycotoxins producing black aspergilli in herbal teas available on the Swiss market Food Control, 26, 157–161. https://doi.org/10.1016/j.foodcont.2012.01.026
    • Werneburg, M., Zerbe, K., Juhas, M., Bigler, L., Stalder, U., Kaech, A., Ziegler, U., Obrecht, D., Eberl, L., & Robinson, J. A. (2012). Inhibition of lipopolysaccharide transport to the outer membrane in Pseudomonas aeruginosa by peptidomimetic antibiotics Chembiochem, 13, 1767–1775. https://doi.org/10.1002/cbic.201200276
    • Simic, B., Hermann, M., Shaw, S. G., Bigler, L., Stalder, U., Dörries, C., Besler, C., Lüscher, T. F., & Ruschitzka, F. (2012). Torcetrapib impairs endothelial function in hypertension European Heart Journal, 33, 1615–1624. https://doi.org/10.1093/eurheartj/ehr348
    • Storari, M., Broggini, G. A. L., Bigler, L., Cordano, E., Eccel, E., De Filippi, R., Gessler, C., & Pertot, I. (2012). Risk assessment of the occurrence of black aspergilli on grapes grown in an alpine region under a climate change scenario European Journal of Plant Pathology, 134, 634–645. https://doi.org/10.1007/s10658-012-0043-0
    • Daum, J. M., Davis, L. R., Bigler, L., & Woodhams, D. C. (2012). Hybrid advantage in skin peptide immune defenses of water frogs (Pelophylax esculentus) at risk from emerging pathogens Infection, Genetics and Evolution, 12, 1854–1864. https://doi.org/10.1016/j.meegid.2012.07.024
    • Ringli, C., Kuhn, B. M., & Bigler, L. (2012). Cell Growth Processes in Arabidopsis thaliana are Modified by Flavonols Chimia, 66, 714. https://doi.org/10.2533/chimia.2012.714

• 2011

  • Journal Article

    • Kuhn, B. M., Geisler, M., Bigler, L., & Ringli, C. (2011). Flavonols accumulate asymmetrically and affect auxin transport in Arabidopsis Plant Physiology, 156, 585–595. https://doi.org/10.1104/pp.111.175976
    • Piccoli, E., Nadai, M., Caretta, C. M., Bergonzini, V., Del Vecchio, C., Ha, H. R., Bigler, L., Dal Zoppo, D., Faggin, E., Pettenazzo, A., Orlando, R., Salata, C., Palù, G., & Baritussio, A. (2011). Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype Biochemical Pharmacology, 82, 1234–1249. https://doi.org/10.1016/j.bbr.2011.03.031

• 2010

  • Journal Article

    • Closa, M., Vranova, E., Bortolotti, C., Bigler, L., Arro, M., Ferrer, A., & Gruissem, W. (2010). The Arabidopsis thaliana FPP synthase isozymes have overlapping and specific functions in isoprenoid biosynthesis, and complete loss of FPP synthase activity causes early developmental arrest The Plant Journal, 63, 512–525. https://doi.org/10.1111/j.1365-313X.2010.04253.x
    • Eichenberger, S., Méret, M., Bienz, S., & Bigler, L. (2010). Decomposition of N-hydroxylated compounds during atmospheric pressure chemical ionization Journal of Mass Spectrometry, 45, 190–197. https://doi.org/10.1002/jms.1703
    • Nikolaev, Y., Deillon, C., Hoffmann, S. R. K., Bigler, L., Friess, S., Zenobi, R., Pervushin, K., Hunziker, P., & Gutte, B. (2010). The leucine zipper domains of the transcription factors GCN4 and c-Jun have ribonuclease activity PLoS ONE, 5, e10765. https://doi.org/10.1371/journal.pone.0010765

• 2009

  • Journal Article

    • Ramel, C., Tobler, M., Meyer, M., Bigler, L., Ebert, M. O., Schellenberg, B., & Dudler, R. (2009). Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate BMC Biochemistry, 10, 26. https://doi.org/10.1186/1471-2091-10-26

  • Habilitation

    • Bigler, L. (2009). Mass spectrometry - recent applications in chemistry, pharmacology and biology (Habilitation, University of Zurich) https://doi.org/10.5167/uzh-20797

• 2008

  • Journal Article

    • Stadler, K., Ha, H. R., Ciminale, V., Spirli, C., Saletti, G., Schiavon, M., Bruttomesso, D., Bigler, L., Follath, F., Pettenazzo, A., & Baritussio, A. (2008). Amiodarone alters late endosomes and inhibits SARS coronavirus infection at a post-endosomal level American Journal of Respiratory Cell and Molecular Biology, 39, 142–149. https://doi.org/10.1165/rcmb.2007-0217OC
    • Schwenninger, S. M., Lacroix, C., Truttmann, S., Jans, C., Spörndli, C., Bigler, L., & Meile, L. (2008). Characterization of low-molecular-weight antiyeast metabolites produced by a food-protective Lactobacillus-Propionibacterium coculture Journal of Food Protection, 71, 2481–2487. https://doi.org/10.4315/0362-028X-71.12.2481
    • Santelia, D., Henrichs, S., Vincenzetti, V., Sauer, M., Bigler, L., Klein, M., Bailly, A., Lee, Y., Friml, J., Geisler, M., & Martinoia, E. (2008). Flavonoids redirect PIN-mediated polar auxin fluxes during root gravitropic responses Journal of Biological Chemistry, 283, 31218–31226. https://doi.org/10.1074/jbc.M710122200
    • Ringli, C., Bigler, L., Kuhn, B. M., Leiber, R. M., Diet, A., Santelia, D., Frey, B., Pollmann, S., & Klein, M. (2008). The modified Flavonol glycosylation profile in the Arabidopsis rol1 mutants results in alterations in plant growth and cell shape formation Plant Cell, 20, 1470–1481. https://doi.org/10.1105/tpc.107.053249

• 2007

  • Journal Article

    • Eichenberger, S., Bigler, L., & Bienz, S. (2007). Structure elucidation of polyamine toxins in the venom of the spider larinioides folium Chimia, 61, 161–164. https://doi.org/10.2533/chimia.2007.161
    • Krauss, J., Härri, S. A., Bush, L., Husi, R., Bigler, L., Power, S. A., & Müller, C. B. (2007). Effects of fertilizer, fungal endophytes and plant cultivar on the performance of insect herbivores and their natural enemies Functional Ecology, 21, 107–116. https://doi.org/10.1111/j.1365-2435.2006.01216.x

• 2005

  • Journal Article

    • Tzouros, M., Chesnov, S., Bienz, S., Hesse, M., & Bigler, L. (2005). New linear polyamine derivatives in spider venoms Toxicon, 46, 350–354. https://doi.org/10.1016/j.toxicon.2005.04.018

• 2004

  • Journal Article

    • Manov, N., Tzouros, M., Bigler, L., & Bienz, S. (2004). Solid-phase synthesis of 15N-labeled acylpentamines as reference compounds for the MS/MS investigation of spider toxins Tetrahedron, 60, 2387–2391. https://doi.org/10.1016/j.tet.2003.12.066
    • Tzouros, M., Manov, N., Bienz, S., & Bigler, L. (2004). Tandem mass spectrometric investigation of acylpolyamines of spider venoms and their 15N-labeled derivatives Journal of the American Society for Mass Spectrometry, 15, 1636–1643. https://doi.org/10.1016/j.jasms.2004.07.020
    • Tzouros, M., Bigler, L., Bienz, S., Hesse, M., Inada, A., Murata, H., Inatomi, Y., Nakanishi, T., & Darnaedi, D. (2004). Two new spermidine alkaloids from Chisocheton weinlandii Helvetica Chimica Acta, 87, 1411–1425. https://doi.org/10.1002/hlca.200490129
    • Fässler, J., Huber, P., Bratovanov, S., Bigler, L., Bild, N., & Bienz, S. (2004). Neighboring-Group participation in the gas phase. Loss of benzaldehyde from [(benzyloxy)methyl]dialkylsilyl-substituted 1,3-dithianes Helvetica Chimica Acta, 78, 1855–1862. https://doi.org/10.1002/hlca.19950780719

• 2002

  • Journal Article

    • Manov, N., Tzouros, M., Chesnov, S., Bigler, L., & Bienz, S. (2002). Solid-Phase Synthesis of Polyamine Spider Toxins and Correlation with the Natural Products by HPLC-MS/MS Helvetica Chimica Acta, 85, 2827–2846. https://doi.org/10.1002/1522-2675(200209)85:9<2827::Aid-Hlca2827>3.0.Co;2-5

• 1995

  • Journal Article

    • Chapeaurouge, A., Bigler, L., Schäfer, A., & Bienz, S. (1995). Correlation of stereoselectivity and ion response in electrospray mass-spectrometry. electrospray ionization-mass spectrometry as a tool to predict chemical behavior? Journal of the American Society for Mass Spectrometry, 6, 207–211. https://doi.org/10.1016/1044-0305(94)00161-R