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Laurent Bigler
Publications
ZORA Publication List
Publications
Journal Article
2025
Guérin, Amandine; Levasseur, Caroline; Herger, Aline; Renggli, Dominik; Sotiropoulos, Alexandros Georgios; Kadler, Gabor; Hou, Xiaoyu; Schaufelberger, Myriam; Meyer, Christian; Wicker, Thomas; Bigler, Laurent; Ringli, Christoph (2025).
Histidine limitation alters plant development and influences the TOR network
Journal of Experimental Botany, 76(4):1085-1098.
2024
Lang, Jakob; Ramos, Sergio E; Reichert, Linus; Amboka, Grace M; Apel, Celina; Chidawanyika, Frank; Detebo, Andargachew; Librán-Embid, Felipe; Meinhof, David; Bigler, Laurent; Schuman, Meredith C (2024).
Push–Pull Intercropping Increases the Antiherbivore Benzoxazinoid Glycoside Content in Maize Leaf Tissue
ACS Agricultural Science & Technology, 4(10):1074-1082.
Jeong, Seungwoo; Schütz, Vadim; Demir, Fatih; Preusche, Matthias; Huesgen, Pitter; Bigler, Laurent; Kovacic, Filip; Gutbrod, Katharina; Dörmann, Peter; Schulz, Margot (2024).
Cyclic Isothiocyanate Goitrin Impairs Lotus japonicus Nodulation, Affects the Proteomes of Nodules and Free Mesorhizobium loti, and Induces the Formation of Caffeic Acid Derivatives in Bacterial Cultures
Plants, 13(20):2897.
Gu, Shaohua; Shao, Yuanzhe; Rehm, Karoline; Bigler, Laurent; Zhang, Di; He, Ruolin; Xu, Ruichen; Shao, Jiqi; Jousset, Alexandre; Friman, Ville-Petri; Bian, Xiaoying; Wei, Zhong; Kümmerli, Rolf; Li, Zhiyuan (2024).
Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways
eLife, 13:RP96719.
Mendo Diaz, Oscar; Patiny, Luc; Tell, Adriana; Hutter, Jules; Knobloch, Marco; Stalder, Urs; Kern, Susanne; Bigler, Laurent; Heeb, Norbert; Bleiner, Davide (2024).
A Quasi Real-Time Evaluation of High-Resolution Mass Spectra of Complex Chlorinated Paraffin Mixtures and Their Transformation Products
Analytical Chemistry, 96(30):12378-12386.
Schiefelbein, Kevin; Lang, Jakob; Schuster, Matthias; Grigglestone, Claire E; Striga, Robin; Bigler, Laurent; Schuman, Meredith C; Zerbe, Oliver; Li, Yanyan; Hartrampf, Nina (2024).
Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides
Journal of the American Chemical Society, 146(25):17261-17269.
Gu, Shaohua; Shao, Yuanzhe; Rehm, Karoline; Bigler, Laurent; Zhang, Di; He, Ruolin; Xu, Ruichen; Shao, Jiqi; Jousset, Alexandre; Friman, Ville-Petri; Bian, Xiaoying; Wei, Zhong; Kümmerli, Rolf; Li, Zhiyuan (2024).
From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways
eLife, 13:RP96719.
Knobloch, Marco C; Hutter, Jules; Diaz, Oscar Mendo; Zennegg, Markus; Vogel, Jean Claude; Durisch, Edith; Stalder, Urs; Bigler, Laurent; Kern, Susanne; Bleiner, Davide; Heeb, Norbert V (2024).
Evolution of chlorinated paraffin and olefin fingerprints in sewage sludge from 1993 to 2020 of a Swiss municipal wastewater treatment plant
Chemosphere, 349:140825.
2023
Mendo Diaz, O; Tell, A; Knobloch, M; Canonica, E; Walder, C; Buser, A M; Stalder, U; Bigler, Laurent; Kern, S; Bleiner, D; Heeb, N V (2023).
Fingerprinting of chlorinated paraffins and their transformation products in plastic consumer products
Chemosphere, 338:139552.
Hofmann, Diana; Thiele, Björn; Siebers, Meike; Rahmati, Mehdi; Schütz, Vadim; Jeong, Seungwoo; Cui, Jiaxin; Bigler, Laurent; Held, Federico; Wu, Bei; Babic, Nikolina; Kovacic, Filip; Hamacher, Joachim; Hölzl, Georg; Dörmann, Peter; Schulz, Margot (2023).
Implications of Below-Ground Allelopathic Interactions of Camelina sativa and Microorganisms for Phosphate Availability and Habitat Maintenance
Plants, 12(15):2815.
2022
Knobloch, Marco C; Mathis, Flurin; Diaz, Oscar Mendo; Stalder, Urs; Bigler, Laurent; Kern, Susanne; Bleiner, Davide; Heeb, Norbert V (2022).
Selective and Fast Analysis of Chlorinated Paraffins in the Presence of Chlorinated Mono-, Di-, and Tri-Olefins with the R-Based Automated Spectra Evaluation Routine (RASER)
Analytical Chemistry, 94(40):13777-13784.
2021
Guan, Pingyin; Zhou, Jianning; Girel, Sergey; Zhu, Xin; Schwab, Marian; Zhang, Kunxi; Wang‐Müller, Qiyan; Bigler, Laurent; Nick, Peter (2021).
Anti‐microtubule activity of the traditional Chinese medicine herb Northern Ban Lan ( Isatis tinctoria ) leads to glucobrassicin
Journal of integrative plant biology, 63(12):2058-2074.
Sieber, Simon; Mathew, Anugraha; Jenul, Christian; Kohler, Tobias; Bär, Max; Carrión, Víctor J; Cazorla, Francisco M; Stalder, Urs; Hsieh, Ya-Chu; Bigler, Laurent; Eberl, Leo; Gademann, Karl (2021).
Mitigation of Pseudomonas syringae virulence by signal inactivation
Science Advances, 7(37):eabg2293.
Schumacher, Isabel; Ndinyanka Fabrice, Tohnyui; Abdou, Marie-Therese; Kuhn, Benjamin M; Voxeur, Aline; Herger, Aline; Roffler, Stefan; Bigler, Laurent; Wicker, Thomas; Ringli, Christoph (2021).
Defects in Cell Wall Differentiation of the Arabidopsis Mutant rol1-2 Is Dependent on Cyclin-Dependent Kinase CDK8
Cells, 10(3):685.
2020
Ozdas, Mehmet S; Shah, Aagam S; Johnson, Paul M; Patel, Nisheet; Marks, Markus; Yasar, Tansel Baran; Stalder, Urs; Bigler, Laurent; von der Behrens, Wolfger; Sirsi, Shashank R; Yanik, Mehmet Fatih (2020).
Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
Nature Communications, 11:4929.
Forster, Yvonne M; Green, Jennifer Leigh; Khatiwada, Apeksha; Liberato, José Luiz; Narayana Reddy, Poli Adi; Salvino, Joseph M; Bienz, Stefan; Bigler, Laurent; dos Santos, Wagner Ferreira; Karklin Fontana, Andréia Cristina (2020).
Elucidation of the Structure and Synthesis of Neuroprotective Low Molecular Mass Components of the Parawixia bistriata Spider Venom
ACS Chemical Neuroscience, 11(11):1573-1596.
Woodhams, Douglas C; Rollins-Smith, Louise A; Reinert, Laura K; Lam, Briana A; Harris, Reid N; Briggs, Cheryl J; Vredenburg, Vance T; Patel, Bhumi T; Caprioli, Richard M; Chaurand, Pierre; Hunziker, Peter; Bigler, Laurent (2020).
Probiotics Modulate a Novel Amphibian Skin Defense Peptide That Is Antifungal and Facilitates Growth of Antifungal Bacteria
Microbial Ecology, 79(1):192-202.
2019
Borjas Nevarez, Rosendo; Kim, Eunja; Childs, Bradley C; Braband, Henrik; Bigler, Laurent; Stalder, Urs; Alberto, Roger; Weck, Philippe F; Poineau, Frederic (2019).
Zirconium chloride molecular species: combining electron impact mass spectrometry and first principles calculations
SN Applied Sciences, 1(5):392.
2018
Childs, Bradley C; Lawler, Keith V; Braband, Henrik; Mast, Daniel S; Bigler, Laurent; Stalder, Urs; Peterson, Derek R; Jansen, Alek; Forster, Paul M; Czerwinski, Kenneth R; Alberto, Roger; Sattelberger, Alfred P; Poineau, Frederic (2018).
The Nature of the Technetium Species Formed During the Oxidation of Technetium Dioxide with Oxygen and Water
European Journal of Inorganic Chemistry, 2018(9):1137-1144.
2017
Niewoehner, Ole; Garcia-Doval, Carmela; Rostøl, Jakob T; Berk, Christian; Schwede, Frank; Bigler, Laurent; Hall, Jonathan; Marraffini, Luciano A; Jinek, Martin (2017).
Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers
Nature, 548(7669):543-548.
Kuhn, Benjamin M; Nodzyński, Tomasz; Errafi, Sanae; Bucher, Rahel; Gupta, Shibu; Aryal, Bibek; Dobrev, Petre; Bigler, Laurent; Geisler, Markus; Zažímalová, Eva; Friml, Jiří; Ringli, Christoph (2017).
Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity
Scientific Reports, 7:41906.
2016
Childs, Bradley C; Braband, Henrik; Lawler, Keith; Mast, Daniel S; Bigler, Laurent; Stalder, Urs; Forster, Paul M; Czerwinski, Kenneth R; Alberto, Roger; Sattelberger, Alfred P; Poineau, Frederic (2016).
Ditechnetium heptoxide revisited: solid-state, gas-phase, and theoretical studies
Inorganic Chemistry, 55(20):10445-10452.
Sasse, Joëlle; Schlegel, Markus; Borghi, Lorenzo; Ullrich, Friederike; Lee, Miyoung; Liu, Guo-Wei; Giner, José-Luis; Kayser, Oliver; Bigler, Laurent; Martinoia, Enrico; Kretzschmar, Tobias (2016).
Petunia hybrida PDR2 is involved in herbivore defense by controlling steroidal contents in trichomes
Plant, Cell & Environment, 39(12):2725-2739.
Pavlovic, Igor; Thakor, Divyeshsinh T; Vargas, Jessica R; McKinlay, Colin J; Hauke, Sebastian; Anstaett, Philipp; Camuña, Rafael C; Bigler, Laurent; Gasser, Gilles; Schultz, Carsten; Wender, Paul A; Jessen, Henning J (2016).
Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo
Nature Communications, 7:10622.
Ruiz-Sola, M Águila; Coman, Diana; Beck, Gilles; Barja, M Victoria; Colinas, Maite; Graf, Alexander; Welsch, Ralf; Rütimann, Philipp; Bühlmann, Peter; Bigler, Laurent; Gruissem, Wilhelm; Rodríguez-Concepción, Manuel; Vranová, Eva (2016).
Arabidopsis GERANYLGERANYL DIPHOSPHATE SYNTHASE 11 is a hub isozyme required for the production of most photosynthesis-related isoprenoids
New Phytologist, 209(1):252-264.
Woodhams, Douglas C; Bell, Sara C; Bigler, Laurent; Caprioli, Richard M; Chaurand, Pierre; Lam, Brianna A; Reinert, Laura K; Stalder, Urs; Vazquez, Victoria M; Schliep, Klaus; Hertz, Andreas; Rollins-Smith, Louise A (2016).
Life history linked to immune investment in developing amphibians
Conservation Physiology, 4(1):cow025.
2015
Salata, Cristiano; Baritussio, Aldo; Munegato, Denis; Calistri, Arianna; Ha, Huy Riem; Bigler, Laurent; Fabris, Fabrizio; Parolin, Cristina; Palu, Giorgio; Mirazimi, Ali (2015).
Amiodarone and metabolite MDEA inhibit Ebola virus infection by interfering with the viral entry process
FEMS Pathogens and Disease, 73(5):ftv032-ftv032.
Semmler, A; Heese, P; Stoffel-Wagner, B; Muschler, M; Heberlein, A; Bigler, L; Prost, J C; Frieling, H; Kornhuber, J; Banger, M; Bleich, S; Hillemacher, T; Linnebank, M (2015).
Alcohol abuse and cigarette smoking are associated with global DNA hypermethylation: results from the German Investigation on Neurobiology in Alcoholism (GINA)
Alcohol, 49(2):97-101.
Chauhan, Harsh; Boni, Rainer; Bucher, Rahel; Kuhn, Benjamin; Buchmann, Gabriele; Sucher, Justine; Selter, Liselotte L; Hensel, Goetz; Kumlehn, Jochen; Bigler, Laurent; Glauser, Gaëtan; Wicker, Thomas; Krattinger, Simon G; Keller, Beat (2015).
The wheat resistance gene Lr34 results in the constitutive induction of multiple defense pathways in transgenic barley
The Plant Journal, 84(1):202-215.
2014
2013
2012
Werneburg, Martina; Zerbe, Katja; Juhas, Mario; Bigler, Laurent; Stalder, Urs; Kaech, Andres; Ziegler, Urs; Obrecht, Daniel; Eberl, Leo; Robinson, John A (2012).
Inhibition of lipopolysaccharide transport to the outer membrane in Pseudomonas aeruginosa by peptidomimetic antibiotics
Chembiochem, 13:1767-1775.
Simic, B; Hermann, M; Shaw, S G; Bigler, L; Stalder, U; Dörries, C; Besler, C; Lüscher, T F; Ruschitzka, F (2012).
Torcetrapib impairs endothelial function in hypertension
European Heart Journal, 33(13):1615-1624.
2011
Piccoli, Elena; Nadai, Matteo; Caretta, Carla M; Bergonzini, Valeria; Del Vecchio, Claudia; Ha, Huy Riem; Bigler, Laurent; Dal Zoppo, Daniele; Faggin, Elisabetta; Pettenazzo, Andrea; Orlando, Rocco; Salata, Cristiano; Palù, Giorgio; Baritussio, Aldo (2011).
Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype
Biochemical Pharmacology, 82:1234-1249.
2010
Nikolaev, Y; Deillon, C; Hoffmann, S R K; Bigler, L; Friess, S; Zenobi, R; Pervushin, K; Hunziker, P; Gutte, B (2010).
The leucine zipper domains of the transcription factors GCN4 and c-Jun have ribonuclease activity
PLoS ONE, 5(5):e10765.
2009
2008
Stadler, K; Ha, H R; Ciminale, V; Spirli, C; Saletti, G; Schiavon, M; Bruttomesso, D; Bigler, L; Follath, F; Pettenazzo, A; Baritussio, A (2008).
Amiodarone alters late endosomes and inhibits SARS coronavirus infection at a post-endosomal level
American Journal of Respiratory Cell and Molecular Biology, 39(2):142-149.
Santelia, D; Henrichs, S; Vincenzetti, V; Sauer, M; Bigler, L; Klein, M; Bailly, A; Lee, Y; Friml, J; Geisler, M; Martinoia, E (2008).
Flavonoids redirect PIN-mediated polar auxin fluxes during root gravitropic responses
Journal of Biological Chemistry, 283(45):31218-31226.
Ringli, C; Bigler, L; Kuhn, B M; Leiber, R M; Diet, A; Santelia, D; Frey, Beat; Pollmann, S; Klein, M (2008).
The modified Flavonol glycosylation profile in the Arabidopsis rol1 mutants results in alterations in plant growth and cell shape formation
Plant Cell, 20(6):1470-1481.
2007
2005
2004
Tzouros, Manuel; Bigler, Laurent; Bienz, Stefan; Hesse, Manfred; Inada, Akira; Murata, Hiroko; Inatomi, Yuka; Nakanishi, Tsutomu; Darnaedi, Dedy (2004).
Two new spermidine alkaloids from Chisocheton weinlandii
Helvetica Chimica Acta, 87(6):1411-1425.
2002
1995
Edited Scientific Work
Habilitation
Master's Thesis