Publications

ZORA Publication List

Publications

• 2016

  • Journal Article

    • García-Domínguez, Patricia; Nevado, Cristina (2016). Au–Pd bimetallic catalysis: the importance of anionic ligands in catalyst speciation. Journal of the American Chemical Society, 138(10):3266-3269.
    • Unzue, Andrea; Lafleur, Karine; Zhao, Hongtao; Zhou, Ting; Dong, Jing; Kolb, Peter; Liebl, Johanna; Zahler, Stefan; Caflisch, Amedeo; Nevado, Cristina (2016). Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation. European journal of medicinal chemistry, 112:347-366.
    • Unzue, Andrea; Xu, Ming; Dong, Jing; Wiedmer, Lars; Spiliotopoulos, Dimitrios; Caflisch, Amedeo; Nevado, Cristina (2016). Fragment-based design of selective nanomolar ligands of the crebbp bromodomain. Journal of Medicinal Chemistry, 59(4):1350-1356.

• 2015

  • Journal Article

    • Xu, Min; Unzue, Andrea; Dong, Jing; Spiliotopoulos, Dimitrios; Nevado, Cristina; Caflisch, Amedeo (2015). Discovery of CREBBP bromodomain inhibitors by high-throughput docking and hit optimization guided by molecular dynamics. Journal of Medicinal Chemistry:2487-2491.
    • Kumar, Roopender; Linden, Anthony; Nevado, Cristina (2015). Luminescent (N^C^C)-Gold(III) Complexes: Stabilized Gold(III) fluorides. Angewandte Chemie Internationale Edition, 54(48):14287-14290.
    • Li, Zhaodong; García-Domínguez, Andres; Nevado, Cristina (2015). Pd-catalyzed stereoselective carboperfluoroalkylation of alkynes. Journal of the American Chemical Society, 137(36):11610-11613.
    • Kong, Wangqing; Fuentes, Noelia; García-Domínguez, Andres; Merino, Estíbaliz; Nevado, Cristina (2015). Stereoselective synthesis of highly functionalized indanes and dibenzocycloheptadienes through complex radical cascade reactions. Angewandte Chemie Internationale Edition, 54(8):2487-2491.
    • Fuentes, Noelia; Kong, Wangqing; Fernández-Sánchez, Luis; Merino, Estibaliz; Nevado, Cristina (2015). Cyclization cascades via N-amidyl radicals toward highly functionalized heterocyclic scaffolds. Journal of the American Chemical Society, 137(2):964-973.

• 2014

  • Journal Article

    • Kong, Wangqing; Merino, Estíbaliz; Nevado, Cristina (2014). Arylphosphonylation and Arylazidation of Activated Alkenes. Angewandte Chemie Internationale Edition, 53(20):5078-5082.
    • Merino, Estíbaliz; Nevado, Cristina (2014). Addition of CF$_3$ across unsaturated moieties: a powerful functionalization tool. Chemical Society reviews, 43(18):6598-6608.
    • Kong, Wangqing; Merino, Estíbaliz; Nevado, Cristina (2014). Divergent reaction mechanisms in the aminofluorination of alkenes. Chimia, 68(6):430-435.
    • Unzue, Andrea; Dong, Jing; Lafleur, Karine; Zhao, Hongtao; Frugier, Emilie; Caflisch, Amedeo; Nevado, Cristina (2014). Pyrrolo[3,2-b]quinoxaline derivatives as types I1/2 and II Eph tyrosine kinase inhibitors: structure-based design, synthesis, and in vivo validation. Journal of Medicinal Chemistry, 57(15):6834-6844.

  • Book Section

    • Merino, Estíbaliz; Fernandez, Luis; Nevado, Cristina (2014). Gold‐Catalyzed Migrations and Ring Expansions. In: Rappoport, Zvi; Liebman, Joel F; Marek, Ilan. Patai's Chemistry of functional groups. Hoboken, New Jersey, 1-72.

• 2013

  • Journal Article

    • Kong, Wangqing; Casimiro, Maria; Fuentes, Noelia; Merino, Estíbaliz; Nevado, Cristina (2013). Metal-free aryltrifluoromethylation of activated alkenes. Angewandte Chemie Internationale Edition, 52(49):13086-13090.
    • Kong, Wangqing; Casimiro, Maria; Merino, Estíbaliz; Nevado, Cristina (2013). Copper-catalyzed one-pot trifluoromethylation/aryl migration/desulfonylation and C(sp2)-N bond formation of conjugated tosyl amides. Journal of the American Chemical Society, 135(39):14480-14483.
    • Merino, Estíbaliz; Nevado, Cristina (2013). On gold catalysis and beyond. Chimia, 67(9):663-668.
    • Lafleur, Karine; Dong, Jing; Huang, Danzhi; Caflisch, Amedeo; Nevado, Cristina (2013). Optimization of inhibitors of the tyrosine kinase EphB4. 2. Cellular potency improvement and binding mode validation by X-ray crystallography. Journal of Medicinal Chemistry, 56(1):84-96.

• 2012

  • Journal Article

    • Linden, Anthony; de Haro, T; Nevado, C (2012). [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene]chloridogold(I). Acta Crystallographica. Section C, Crystal Structure Communications, 68(1):m1-m3.

• 2010

  • Journal Article

    • Huang, D; Zhou, T; Lafleur, K; Nevado, C; Caflisch, A (2010). Kinase selectivity potential for inhibitors targeting the ATP binding site: A network analysis. Bioinformatics, 26(2):198-204.

• 2009

  • Journal Article

    • Huang, X; De Haro, T; Nevado, C (2009). Gold-catalyzed stereocontrolled synthesis of 2,3-bis(acetoxy)-1,3-dienes. Chemistry - A European Journal, 15(24):5904-5908.
    • Cribiú, R; Jäger, C; Nevado, C (2009). Syntheses and biological evaluation of iriomoteolide 3a and analogues. Angewandte Chemie Internationale Edition, 48(46):8780-8783.
    • Lafleur, K; Huang, D; Zhou, T; Caflisch, A; Nevado, C (2009). Structure-based optimization of potent and selective inhibitors of the tyrosine kinase erythropoietin producing human hepatocellular carcinoma receptor B4 (EphB4). Journal of Medicinal Chemistry, 52(20):6433-6446.

• 2008

  • Journal Article

    • Nieto-Oberhuber, C; Muñoz, M P; López, S; Jiménez-Núñez, E; Nevado, C; Herrero-Gómez, E; Raducan, M; Echavarren, A M (2008). Corrigendum: Gold(I)-catalyzed cyclizations of 1,6-enynes: alkoxycyclizations and exo/endo skeletal rearrangements. Chemistry - A European Journal, 14(17):5096.
    • Zou, Y; Garayalde, D; Wang, Q; Nevado, Cristina; Goeke, A (2008). Gold-catalyzed cycloisomerization of cyclopropyl alkynyl acetates: a versatile approach to 5-, 6-, and 7-membered carbocycles. Angewandte Chemie Internationale Edition, 47(52):10110-10113.

Pagination