Jason Holland receives Grant by Schweizer Krebsliga
Jason Holland's project "Harnessing androgen receptor signalling for imaging protein degradation therapy in prostate cancer', was one of 16 basic science applications to receive approval by the Schweizer Krebsliga.
The project aims to develop radioactive imaging agents to measure changes in cellular signalling in prostate cancer. Work will begin in 2018 with a PhD student synthesising new radiotracers for positron emission tomography (PET) imaging of biomarkers associated with androgen receptor signalling. Cellular studies and PET imaging in animal models of human prostate cancer will be used to evaluate the effects of a new class of drugs that target and induce catalytic degradation of key proteins that regulate DNA transcription. By monitoring the downstream effects of drug action in vitro and in vivo, the goal is to define more accurate dose-response profiles that will allow us to optimise drug efficacy and reduce side-effects for individual patients.
More news
- Catalysis and Design - Jochen Block-Prize 2019 for Sandra Luber
- Very important paper by Vladimir Rybkin in Angew. Chem. Int. Ed.
- Sandra Luber honored with Carl-Duisberg-Gedächtnispreis
- Insect Antibiotic Provides New Way to Eliminate Bacteria
- New paper by Roland K.O. Sigel in PNAS
- Nathan Luedtke appointed as Full Professor
- Diastereoselective Ullmann Coupling to Bishelicenes by Surface Topochemistry
- Eco-Friendly Nanoparticles for Artificial Photosynthesis
- Eva Freisinger appointed as Associate Professor ad personam
- Peter Ham is the 2018 Ellis R. Lippincott Award Recipient
- New Paper by Michal Juríček in JACS
- Cristina Nevado together with three other research groups from UZH gets an SNF Sinergia Grant
- New paper by Jason Holland: Chemical kinetics of radiolabelling reactions
- LightChEC team discovers new autocatalytic burning mechanism of polycyclic aromatic hydrocarbons
- Sandra Luber wins Werner Prize 2018
- New Method Speeds Up Development of Medication
- Sandra Luber wins Robin Hochstrasser Young Investigator Award
- Peter Hamm honored by The Optical Society (OSA)
- Sandra Luber wins Hellmann-Preis
- Andrés García wins Award for Best Oral Presentation
- IBM Research Forschungspreis 2017 for Corina Keller
- Roland Sigel: The new Dean of the Faculty of Science
- Doktorandentag 2017
- Roger Alberto wins Humboldt Research Award
- Ralph Koitz and Mauro del Ben awarded with the IBM Research Prize
- Greta Patzke wins the Credit Suisse Award for Best Teaching 2017
- Oliver Zerbe publishes "hot paper " in Angewandte Chemie
- Kathrin Fenner: Guest Editor of themed issue of "Environmental Science: Processes & Impacts"
- Exciting new science by Madhavi Krishnan
- Two new SNSF-Professorships at the DoC: Sandra Luber and Michal Juricek
- Sandra Luber receives Clara Immerwahr Award 2017
- David Tilley publishes important advances for solar water splitting
- Jason Holland appointed to two editorial boards
- Lecture Awards for Angelo Frei and Lucas Prieto
- Laurent Bigler's paper on the Cover of Plant Cell Environment
- PD Dr. Kathrin Fenner appointed as Professor ad personam for environmental chemistry
- Prof. Cristina Nevado selected as Senior Editor for ACS Central Science
- Assistant professor Madhavi Krishnan receives ERC Consolidator Grant
- Three awards for UZH students at the SCS Fall Meeting 2016
- Nobel Prize Laureate Jean-Pierre Sauvage is Honorory Doctor of UZH
- ERC Consolidator Grant
- Nernst-Haber-Bodensteinpreis 2016
- Outstanding Paper
- Royal Society of Chemistry Prize
- News Archive