Publications

ZORA Publication List

Publications

• 2026

  • Journal Article

    • Buso, G., Mirault, T., Schlager, O., Heiss, C., Boc, V., Brodmann, M., Ageno, W., Barco, S. L., Madaric, J., Belch, J., Müller, O. J., Freisinger, E., Behrendt, C.-A., Korosoglou, G., Czihal, M., Mazzolai, L., Rammos, C., & editorial board of Vasa. (2026). The year in vascular medicine: Highlights in Vasa - European Journal of Vascular Medicine 2025 Vasa, 55(1), 1–5. https://doi.org/10.1024/0301-1526/a001257

• 2025

  • Journal Article

    • Karunaratne, R., Willems, E. P., Zerbe, O., & Freisinger, E. (2025). Elucidating the metalation pathway of the Ec-1 metallothionein βE-domain: Insights into ZnII binding and protein folding Journal of Inorganic Biochemistry, 270, 112931. https://doi.org/10.1016/j.jinorgbio.2025.112931

• 2024

  • Edited Scientific Work

    • Sigel, A., Sigel, H., Freisinger, E., Sigel, R. K. O., & Bettencourt-Dias, A. de (Eds.). (2024). Metal-Containing Molecules and Nanomaterials: From Diagnosis to Therapy (Vol. 26). CRC Press, Taylor & Francis Group.
    • Sigel, A., Sigel, H., Freisinger, E., Sigel, R. K. O., & Geraldes, C. F. G. C. (Eds.). (2024). Lanthanide and other Transition Metal Ion Complexes and Nanoparticles in Magnetic Resonance Imaging (Vol. 27). CRC Press.

• 2023

  • Journal Article

    • Heiss, C., Barco, S., Behrendt, C.-A., Brodmann, M., Freisinger, E., Partovi, S., Rammos, C., Müller, O. J., & Editorial board of Vasa. (2023). The year in vascular medicine: Highlights in Vasa - European Journal of Vascular Medicine 2022. Vasa, 52, 3–5. https://doi.org/10.1024/0301-1526/a001048

• 2022

  • Journal Article

    • Łuczkowski, M., Padjasek, M., Ba Tran, J., Hemmingsen, L., Kerber, O., Habjanič, J., Freisinger, E., & Krężel, A. (2022). An Extremely Stable Interprotein Tetrahedral Hg(Cys)$_{4}$ Core Forms in the Zinc Hook Domain of Rad50 Protein at Physiological pH Chemistry, 28, e202202738. https://doi.org/10.1002/chem.202202738

  • Book Section

    • Hafner, J. (2022). Arteriolosklerose In U. Hoffmann, N. Weiss, M. Czihal, B. Linnemann, & E. Freisinger (Eds.), Klinische Angiologie (pp. 1–10). Springer. https://doi.org/10.1007/978-3-662-61379-5_90-1

• 2021

  • Journal Article

    • Pullen, S., Hegmans, A., Hiller, W. G., Platzek, A., Freisinger, E., & Lippert, B. (2021). On the Heterogeneous Nature of Cisplatin‐1‐Methyluracil Complexes: Coexistence of Different Aggregation Modes and Partial Loss of NH 3 Ligands as Likely Explanation ChemistryOpen, 10, 28–45. https://doi.org/10.1002/open.202000317

• 2020

  • Journal Article

    • Perinelli, M., Tegoni, M., & Freisinger, E. (2020). Different Behavior of the Histidine Residue toward Cadmium and Zinc in a Cadmium-Specific Metallothionein from an Aquatic Fungus Inorganic Chemistry, 59, 16988–16997. https://doi.org/10.1021/acs.inorgchem.0c02171
    • Salim, A., Chesnov, S., & Freisinger, E. (2020). Metallation pathway of a plant metallothionein: Cicer arietinum MT2 Journal of Inorganic Biochemistry, 210, 111157. https://doi.org/10.1016/j.jinorgbio.2020.111157
    • Habjanič, J., Mathew, A., Eberl, L., & Freisinger, E. (2020). Deciphering the Enigmatic Function of Pseudomonas Metallothioneins Frontiers in Microbiology, 11, 1709–1709. https://doi.org/10.3389/fmicb.2020.01709
    • Habjanič, J., Chesnov, S., Zerbe, O., & Freisinger, E. (2020). Impact of naturally occurring serine/cysteine variations on the structure and function of Pseudomonas metallothioneins Metallomics, 12, 23–33. https://doi.org/10.1039/c9mt00213h

  • Book Section

    • Zhao, M., Börner, R., Sigel, R. K. O., & Freisinger, E. (2020). Site-Specific Dual-Color Labeling of Long RNAs In T. Heise (Ed.), RNA Chaperones (No. 2106; pp. 253–270). Springer. https://doi.org/10.1007/978-1-0716-0231-7_16

• 2019

  • Journal Article

    • Steffen, F. D., Börner, R., Freisinger, E., & Sigel, R. K. O. (2019). Stick, Flick, Click: DNA-guided Fluorescent Labeling of Long RNA for Single-molecule FRET Chimia, 73, 257–261. https://doi.org/10.2533/chimia.2019.257
    • Freisinger, E., & Sigel, R. K. O. (2019). The Bioinorganic Periodic Table Chimia, 73, 185–193. https://doi.org/10.2533/chimia.2019.185

• 2018

  • Journal Article

    • Habjanič, J., Zerbe, O., & Freisinger, E. (2018). A histidine-rich Pseudomonas metallothionein with a disordered tail displays higher binding capacity for cadmium than zinc Metallomics, 10, 1415–1429. https://doi.org/10.1039/c8mt00193f
    • Cabral, A. C. S., Jakovleska, J., Deb, A., Penner-Hahn, J. E., Pecoraro, V. L., & Freisinger, E. (2018). Further insights into the metal ion binding abilities and the metalation pathway of a plant metallothionein from Musa acuminata Journal of Biological Inorganic Chemistry, 23, 91–107. https://doi.org/10.1007/s00775-017-1513-9
    • Zhao, M., Steffen, F. D., Börner, R., Schaffer, M. F., Sigel, R. K. O., & Freisinger, E. (2018). Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy Nucleic Acids Research, 46, e13–e13. https://doi.org/10.1093/nar/gkx1100
    • Freisinger, E., & Sigel, R. K. O. (2018). Celebrating Helmut Sigel Journal of Biological Inorganic Chemistry, 23, 1–5. https://doi.org/10.1007/s00775-017-1523-7

• 2017

  • Journal Article

    • Cao, Q., Li, Y., Freisinger, E., Qin, P. Z., Sigel, R. K. O., & Mao, Z.-W. (2017). G-quadruplex DNA targeted metal complexes acting as potential anticancer drugs Inorganic Chemistry Frontiers, 4, 10–32. https://doi.org/10.1039/C6QI00300A

• 2016

  • Journal Article

    • Tarasava, K., Chesnov, S., & Freisinger, E. (2016). Oxidation of the N-terminal domain of the wheat metallothionein Ec-1 leads to the formation of three distinct disulfide bridges Biopolymers, 106, 295–308. https://doi.org/10.1002/bip.22849
    • Tarasava, K., Loebus, J., & Freisinger, E. (2016). Localization and Spectroscopic Analysis of the Cu(I) Binding Site in Wheat Metallothionein Ec-1 International Journal of Molecular Sciences, 17, 371. https://doi.org/10.3390/ijms17030371
    • Egloff, D., Oleinich, I. A., Zhao, M., König, S. L. B., Sigel, R. K. O., & Freisinger, E. (2016). Sequence-specific post-synthetic oligonucleotide labeling for single-molecule fluorescence applications ACS Chemical Biology, 11, 2558–2567. https://doi.org/10.1021/acschembio.6b00343

• 2015

  • Journal Article

    • Siebel, S., Dammann, C., Sanz Miguel, P. J., Drewello, T., Kampf, G., Teubner, N., Bednarski, P. J., Freisinger, E., & Lippert, B. (2015). Analogues of Cis- and Transplatin with a Rich Solution Chemistry:cis-[PtCl2(NH3)(1-MeC-N3)] andtrans-[PtI2(NH3)(1-MeC-N3)] Chemistry, 21, 17827–17843. https://doi.org/10.1002/chem.201502691
    • Egloff, D., Oleinich, I. A., & Freisinger, E. (2015). Sequence-Specific Generation of 1,N6-Ethenoadenine and 3,N4-Ethenocytosine in Single-Stranded Unmodified DNA ACS Chemical Biology, 10, 547–553. https://doi.org/10.1021/cb500497p
    • Tarasava, K., & Freisinger, E. (2015). Investigating the influence of histidine residues on the metal ion binding ability of the wheat metallothionein γ-Ec-1 domain Journal of Inorganic Biochemistry, 153, 197–203. https://doi.org/10.1016/j.jinorgbio.2015.08.009
    • Lüth, M. S., Freisinger, E., Kampf, G., Garijo Anorbe, M., Griesser, R., Operschall, B. P., Sigel, H., & Lippert, B. (2015). Connectivity patterns and rotamer states of nucleobases determine acid–base properties of metalated purine quartets Journal of Inorganic Biochemistry, 148, 93–104. https://doi.org/10.1016/j.jinorgbio.2015.02.004
    • Freisinger, E., & Sigel, R. K. O. (2015). Preface for the JIB Special Issue for the 12th European Biological Inorganic Chemistry Conference (EuroBIC 12) in Zurich, Switzerland, August 24–28, 2014 Journal of Inorganic Biochemistry, 148, 1. https://doi.org/10.1016/j.jinorgbio.2015.06.013

  • Book Section

    • Nies, D. H., Freisinger, E., & Krauss, G.-J. (2015). Excess of metals In G.-J. Krauss & D. H. Nies (Eds.), Ecological Biochemistry: Environmental and Interspecies Interactions (pp. 237–257). Wiley-VCH. https://doi.org/10.1002/9783527686063.ch12
    • Nies, D. H., Freisinger, E., & Krauss, G.-J. (2015). Excess of metals In G.-J. Krauss & D. H. Nies (Eds.), Ecological Biochemistry: Environmental and Interspecies Interactions (pp. 237–257). Wiley-VCH. https://doi.org/10.1002/9783527686063.ch12

• 2014

  • Journal Article

    • Freisinger, Eva; Sigel, Roland K O (2014). Preface Journal of Biological Inorganic Chemistry, 19(S2):699.
    • Tarasava, K., & Freisinger, E. (2014). An optimized intein-mediated protein ligation approach for the efficient cyclization of cysteine-rich proteins Protein Engineering, Design & Selection, 27, 481–488. https://doi.org/10.1093/protein/gzu048

  • Habilitation

    • Freisinger, E. (2014). Spectroscopic and structural investigations of plant metallothioneins (Habilitation, University of Zurich)

• 2013

  • Journal Article

    • Radunsky, C., Megger, D. A., Hepp, A., Kösters, J., Freisinger, E., & Müller, J. (2013). A family of hydrazone-based nucleosides for use in metal-mediated base pairs Zeitschrift Für Anorganische Und Allgemeine Chemie, 639, 1621–1627. https://doi.org/10.1002/zaac.201300061
    • Phongtongpasuk, S., Paulus, S., Schnabl, J., Sigel, R. K. O., Spingler, B., Hannon, M. J., & Freisinger, E. (2013). Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junction Angewandte Chemie Internationale Edition, 52, 11513–11516. https://doi.org/10.1002/anie.201305079
    • Tarasava, K., Johannsen, S., & Freisinger, E. (2013). Solution structure of the circular γ-domain analog from the wheat metallothionein Ec-1 Molecules, 18, 14414–14429. https://doi.org/10.3390/molecules181114414
    • Freisinger, E., & Vasak, M. (2013). Cadmium in metallothioneins Metal Ions in Life Sciences, 11, 339–371. https://doi.org/10.1007/978-94-007-5179-8_11
    • Phongtongpasuk, S., Paulus, S., Schnabl, J., Sigel, R. K. O., Spingler, B., Hannon, M. J., & Freisinger, E. (2013). Binding of a Designed Anti-Cancer Drug to the Central Cavity of an RNA Three-Way Junction Angewandte Chemie, 125, 11727–11730. https://doi.org/10.1002/ange.201305079
    • Loebus, J., Leitenmaier, B., Meissner, D., Braha, B., Krauss, G.-J., Dobritzsch, D., & Freisinger, E. (2013). The major function of a metallothionein from the aquatic fungus Heliscus lugdunensis is cadmium detoxification Journal of Inorganic Biochemistry, 127, 253–260. https://doi.org/10.1016/j.jinorgbio.2013.06.001
    • Wan, X., & Freisinger, E. (2013). Incorporation of sulfide ions into the cadmium(II)-thiolate cluster of Cicer arietinum metallothionein2 Inorganic Chemistry, 52, 785–792. https://doi.org/10.1021/ic301907j
    • Wan, X., Schicht, O., & Freisinger, E. (2013). Copper(I) coordination by two plant metallothioneins Zeitschrift Für Anorganische Und Allgemeine Chemie, 639, 1365–1369. https://doi.org/10.1002/zaac.201300096
    • Huber, T., & Freisinger, E. (2013). Sulfide ions as modulators of metal–thiolate cluster size in a plant metallothionein Dalton Transactions, 42, 8878–8889. https://doi.org/10.1039/C3DT32438A
    • Peroza, E. A., dos Santos Cabral, A., Wan, X., & Freisinger, E. (2013). Metal ion release from metallothioneins: proteolysis as an alternative to oxidation Metallomics, 5, 1204–1214. https://doi.org/10.1039/C3MT00079F

• 2012

  • Journal Article

    • Donghi, D., Johannsen, S., Sigel, R. K. O., & Freisinger, E. (2012). NMR spectroscopy in bioinorganic chemistry Chimia, 66, 791–797. https://doi.org/10.2533/Chimia.2012.791
    • Seubert, K., Böhme, D., Kösters, J., Shen, W.-Z., Freisinger, E., & Müller, J. (2012). N-Methyl-2,2’-dipicolylamine domplexes as potential models for metal-mediated base pairs Zeitschrift Für Anorganische Und Allgemeine Chemie, 638, 1761–1767. https://doi.org/10.1002/zaac.201200089

• 2011

  • Journal Article

    • Freisinger, E. (2011). Structural features specific to plant metallothioneins Journal of Biological Inorganic Chemistry, 16, 1035–1045. https://doi.org/10.1007/s00775-011-0801-z
    • Loebus, J., Peroza, E. A., Blüthgen, N., Fox, T., Meyer-Klaucke, W., Zerbe, O., & Freisinger, E. (2011). Protein and metal cluster structure of the wheat metallothionein domain gamma-Ec-1: the second part of the puzzle Journal of Biological Inorganic Chemistry, 16, 683–694. https://doi.org/10.1007/s00775-011-0770-2
    • Galstyan, A., Sanz Miguel, P. J., Wolf, J., Freisinger, E., & Lippert, B. (2011). Discrete Molecular Squares {[(en)M(CN)]4}4+ Derived from [(en)M(CN)2] (M = PtII, PdII) European Journal of Inorganic Chemistry, 2011, 1649–1656. https://doi.org/10.1002/ejic.201001216
    • Galstyan, A., Shen, W. Z., Freisinger, E., Alkam, H., Hiller, W., Sanz Miguel, P. J., Schürmann, M., & Lippert, B. (2011). Supramolecular Isomerism of 2,2′-Bipyrazine Complexes with cis-(NH3)2PtII: Ligand Rotational State and Sequential Orientation Determine the 3D Shape of Metallacycles Chemistry, 17, 10771–10780. https://doi.org/10.1002/chem.201101381

• 2010

  • Journal Article

    • Freisinger, E. (2010). The metal-thiolate clusters of plant metallothioneins Chimia, 64, 217–224. https://doi.org/10.2533/chimia.2010.217

Pagination