Home
Research
Bernhard Spingler
Publications
ZORA Publication List
Publications
Journal Article
2013
Patra, M., Hess, J., Konatschnig, S., Spingler, B., & Gasser, G. (2013).
Synthesis of Ferrocenyl and Ruthenocenyl Thioamide derivatives using a single-step three-component reaction
Organometallics, 32, 6098–6105. https://doi.org/10.1021/om400715m
Patra, M., Ingram, K., Pierroz, V., Ferrari, S., Spingler, B., Gasser, R. B., Keiser, J., & Gasser, G. (2013).
[(η(6)-Praziquantel)Cr(CO)3] derivatives with remarkable in vitro anti-schistosomal activity
Chemistry, 19, 2232–2235. https://doi.org/10.1002/chem.201204291
Oetterli, R. M., Prieto, L., Spingler, B., & Zelder, F. (2013).
Synthesis of a B ring opened 7,8-seco-Vitamin B12Derivative with Grob fragmentation
Organic Letters, 15, 4630–4633. https://doi.org/10.1021/ol401572j
Patra, M., Joshi, T., Pierroz, V., Ingram, K., Kaiser, M., Ferrari, S., Spingler, B., Keiser, J., & Gasser, G. (2013).
DMSO-Mediated ligand dissociation: renaissance for biological activity of n-heterocyclic-[Ru(η(6) -arene)Cl2 ] Drug Candidates
Chemistry, 14768–14772. https://doi.org/10.1002/chem.201303341
Car, P.-E., Spingler, B., Weyeneth, S., Patscheider, J., & Patzke, G. R. (2013).
All-inorganic 1D chain-based architecture of a novel dimanganese-substituted Keggin polyoxotungstate
Polyhedron, 52, 151–158. https://doi.org/10.1016/j.poly.2012.10.021
2012
Huber, W., Broehler, P., Waetjen, W., Frank, W., Spingler, B., & Kunz, P. C. (2012).
Cytotoxicity of ruthenium(II) piano-stool complexes with imidazole-based PN ligands
Journal of Organometallic Chemistry, 717, 187–194. https://doi.org/10.1016/j.jorganchem.2012.06.027
Huber, W., Linder, R., Niesel, J., Schatzschneider, U., Spingler, B., & Kunz, P. C. (2012).
A Comparative Study of Tricarbonylmanganese Photoactivatable CO Releasing Molecules (PhotoCORMs) by Using the Myoglobin Assay and Time-Resolved IR Spectroscopy
European Journal of Inorganic Chemistry, 2012, 3140–3146. https://doi.org/10.1002/ejic.201200115
Kunz, P. C., Thiel, I., Noffke, A. L., Reiss, G. J., Mohr, F., & Spingler, B. (2012).
Ruthenium piano-stool complexes bearing imidazole-based PN ligands
Journal of Organometallic Chemistry, 697, 33–40. https://doi.org/10.1016/j.jorganchem.2011.10.006
Da Pieve, C., & Spingler, B. (2012).
Nickel and cobalt complexes of 15,15-disubstituted 1,4,7,10,13-pentaazacyclohexadecane-14,16-dione ligands
Inorganica Chimica Acta, 380, 230–235. https://doi.org/10.1016/j.ica.2011.09.004
Can, D., N’Dongo, H. W. P., Spingler, B., Schmutz, P., Raposinho, P., Santos, I., & Alberto, R. (2012).
The (Cp)M(CO)3] (M=Re, 99mTc) building block for imaging agents and bioinorganic probes: Perspectives and limitations
Chemistry & Biodiversity, 9, 1849–1866. https://doi.org/10.1002/cbdv.201200076
Sulieman, S., Can, D., Mertens, J., N’Dongo, H. W. P., Liu, Y., Schmutz, P., Bauwens, M., Spingler, B., & Alberto, R. (2012).
Cyclopentadienyl-Based Amino Acids (Cp-aa) As Phenylalanine Analogues for Tumor Targeting: Syntheses and Biological Properties of (Cp-aa)M(CO)(3)](M = Mn, Re, Tc-99m)
Organometallics, 31, 6880–6886. https://doi.org/10.1021/om300695k
Richter, M., Karschin, A., Spingler, B., Kunz, P. C., Meyer-Zaika, W., & Klaeui, W. (2012).
Stabilisation of water - soluble platinum nanoparticles by phosphonic acid derivatives
Dalton Transactions, 41, 3407–3413. https://doi.org/10.1039/c2dt12071b
Patra, M., Ingram, K., Pierroz, V., Ferrari, S., Spingler, B., Keiser, J., & Gasser, G. (2012).
Ferrocenyl Derivatives of the Anthelmintic Praziquantel: Design, Synthesis, and Biological Evaluation
Journal of Medicinal Chemistry, 55, 8790–8798. https://doi.org/10.1021/jm301077m
Braband, H., Imstepf, S., Benz, M., Spingler, B., & Alberto, R. (2012).
Combining bifunctional chelator with (3+2)-Cycloaddition approaches: Synthesis of dual-function technetium complexes
Inorganic Chemistry, 51, 4051–4057. https://doi.org/10.1021/ic202212e
Can, D., Spingler, B., Schmutz, P., Mendes, F., Raposinho, P., Fernandes, C., Carta, F., Innocenti, A., Santos, I., Supuran, C. T., & Alberto, R. (2012).
[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, Arylsulfamide, and Arylsulfamate conjugates for selective targeting of Human carbonic Anhydrase IX
Angewandte Chemie Internationale Edition, 51, 3354–3357. https://doi.org/10.1002/anie.201107333
2011
Wetzel, C., Kunz, P. C., Thiel, I., & Spingler, B. (2011).
Gold(I) Catalysts with Bifunctional P, N Ligands
Inorganic Chemistry, 50, 7863–7870. https://doi.org/10.1021/ic2011259
Noffke, A. L., Bongartz, M., Wätjen, W., Böhler, P., Spingler, B., & Kunz, P. C. (2011).
Synthesis, X-ray crystal structure and cytotoxicity of a new tetranuclear ruthenium arene complex
Journal of Organometallic Chemistry, 696, 1096–1101. https://doi.org/10.1016/j.jorganchem.2010.10.042
Wetzel, C., Kunz, P. C., Kassack, M. U., Hamacher, A., Böhler, P., Watjen, W., Ott, I., Rubbiani, R., & Spingler, B. (2011).
Gold(i) complexes of water-soluble diphos-type ligands: Synthesis, anticancer activity, apoptosis and thioredoxin reductase inhibition
Dalton Transactions, 40, 9212–9220. https://doi.org/10.1039/c1dt10368g
Ni, L., Hussain, F., Spingler, B., Weyeneth, S., & Patzke, G. R. (2011).
Lanthanoid-containing open wells–Dawson silicotungstates: Synthesis, crystal structures, and properties
Inorganic Chemistry, 50, 4944–4955. https://doi.org/10.1021/ic2001943
Kunz, P. C., Wetzel, C., Kögel, S., Kassack, M. U., & Spingler, B. (2011).
[(C3H4N2)2Au]Cl—a bis protic gold(i)-NHC
Dalton Transactions, 40, 35–37. https://doi.org/10.1039/c0dt01089h
2010
Mindt, T. L., Struthers, H., Spingler, B., Brans, L., Tourwe, D., Garcia-Garayoa, E., & Schibli, R. (2010).
Molecular assembly of multifunctional Tc-99m radiopharmaceuticals using “clickable” amino acid derivatives. ChemMedChem, 5, 2026–2038.
https://doi.org/10.1002/cmdc.201000342
Pitchumony, T. S., Spingler, B., Motterlini, R., & Alberto, R. (2010).
Syntheses, structural characterization and CO releasing properties of boranocarbonate H3BCO2H](-) derivatives
Organic & Biomolecular Chemistry, 8, 4849–4854. https://doi.org/10.1039/c0ob00099j
Kunz, P. C., Wetzel, C., Bongartz, M., Noffke, A. L., & Spingler, B. (2010).
Novel multitopic diphos-type ligands
Journal of Organometallic Chemistry, 695, 1891–1897. https://doi.org/10.1016/j.jorganchem.2010.04.028
Braband, H., Imstepf, S., Felber, M., Spingler, B., & Alberto, R. (2010).
Triazacyclohexane (tach) complexes of high-valent rhenium: syntheses of [(R(3)tach)ReO(3)](+) (R = -CH(3), -CH(2)C(6)H(5)) and its substitution reactions
Inorganic Chemistry, 49, 1283–1285. https://doi.org/10.1021/ic902114p
N’Dongo, H. W. P., Raposinho, P. D., Fernandes, C., Santos, I., Can, D., Schmutz, P., Spingler, B., & Alberto, R. (2010).
Preparation and biological evaluation of cyclopentadienyl-based 99mTc-complexes [(Cp-R)99mTc(CO)3] mimicking benzamides for malignant melanoma targeting
Nuclear Medicine and Biology, 37, 255–264. https://doi.org/10.1016/j.nucmedbio.2009.11.006
Struthers, H., Viertl, D., Kosinski, M., Spingler, B., Buchegger, F., & Schibli, R. (2010).
Charge dependent substrate activity of C3’ and N3 functionalized, organometallic Technetium and Rhenium-labeled thymidine derivatives toward human thymidine kinase 1. Bioconjugate Chemistry, 21, 622–634.
https://doi.org/10.1021/bc900380n
Liu, Y., Oliveira, B. L., Correia, J. D. G., Santos, I. C., Santos, I., Spingler, B., & Alberto, R. (2010).
Syntheses of bifunctional 2,3-diamino propionic acid-based chelators as small and strong tripod ligands for the labelling of biomolecules with (99m)Tc
Organic & Biomolecular Chemistry, 8, 2829–2839. https://doi.org/10.1039/c002796k
2009
Peindy N’Dongo, H. W., Liu, Y., Can, D., Schmutz, P., Spingler, B., & Alberto, R. (2009).
Aqueous syntheses of [(Cp-R)M(CO)3] type complexes (Cp = cyclopentadienyl, M = Mn, 99mTc, Re) with bioactive functionalities
Journal of Organometallic Chemistry, 694, 981–987. https://doi.org/10.1016/j.jorganchem.2008.12.006
Spingler, B., Da Pieve, C., Medina-Molner, A., Antoni, P. M., & Santangelo, M. G. (2009).
Interaction of Novel Metal Complexes with DNA: Synthetic and Structural Aspects
Chimia, 63, 153–156. https://doi.org/10.2533/chimia.2009.153
Michailovski, A., Hussain, F., Spingler, B., Wagler, J., & Patzke, G. R. (2009).
Hydrothermal structure control of polyoxofluoromolybdates(VI)
Crystal Growth & Design, 9, 755–765. https://doi.org/10.1021/cg800265q
Kunz, P. C., Huber, W., Rojas, A., Schatzschneider, U., & Spingler, B. (2009).
Tricarbonylmanganese(I) and –rhenium(I) complexes of imidazol-based phosphane ligands: influence of the substitution pattern on the CO release properties
European Journal of Inorganic Chemistry, 2009, 5358–5366. https://doi.org/10.1002/ejic.200900650
Kunz, P. C., Kassack, M. U., Hamacher, A., & Spingler, B. (2009).
Imidazole-based phosphane gold(I) complexes as potential agents for cancer treatment: Synthesis, structural studies and antitumour activity
Dalton Transactions, 2009, 7741–7747. https://doi.org/10.1039/b902748c
Kunz, P. C., Berghahn, M., Brückmann, N. E., Dickmeis, M., Kettel, M., & Spingler, B. (2009).
Functionalised tris(pyrazolyl)methane ligands and Re(CO)3 complexes thereof
Zeitschrift Für Anorganische Und Allgemeine Chemie, 35, 471–478. https://doi.org/10.1002/zaac.200801298
Hussain, F., Spingler, B., Conrad, F., Speldrich, M., Kögerler, P., Boskovic, C., & Patzke, G. R. (2009).
Caesium-templated lanthanoid-containing polyoxotungstates
Dalton Transactions, 2009, 4423–4425. https://doi.org/10.1039/b902077b
2008
Ruiz-Sánchez, P., Mundwiler, S., Spingler, B., Buan, N. R., Escalante-Semerena, J. C., & Alberto, R. (2008).
Syntheses and characterization of vitamin B12-Pt(II) conjugates and their adenosylation in an enzymatic assay
Journal of Biological Inorganic Chemistry, 13, 335–347. https://doi.org/10.1007/s00775-007-0329-4
Liu, Y., Spingler, B., Schmutz, P., & Alberto, R. (2008).
Metal-mediated retro Diels-Alder of dicyclopentadiene derivatives: a convenient synthesis of [(Cp-R)M(CO)3] (M = 99mTc, Re) complexes
Journal of the American Chemical Society, 130, 1554–1555. https://doi.org/10.1021/ja077741l
Tooyama, Y., Braband, H., Spingler, B., Abram, U., & Alberto, R. (2008).
High-valent technetium complexes with the [(99)TcO(3)](+) core from in situ prepared mixed anhydrides of [(99)TcO(4)](-) and their reactivities
Inorganic Chemistry, 47, 257–264. https://doi.org/10.1021/ic701908q
2007
Medina-Molner, A., Blacque, O., & Spingler, B. (2007).
The synthesis of 1,2-bis(1,5,9-triazacyclododecyl)ethane: A showcase for the importance of the linker length within bis(alkylating) reagents
Organic Letters, 9, 4829–4831. https://doi.org/10.1021/ol7021627
Santangelo, M. G., Medina-Molner, A., Schweiger, A., Mitrikas, G., & Spingler, B. (2007).
Structural analysis of Cu(II) ligation to the 5’-GMP nucleotide by pulse EPR spectroscopy. Journal of Biological Inorganic Chemistry, 12, 767–775.
https://doi.org/10.1007/s00775-007-0230-1
Spingler, B., Mundwiler, S., Ruiz-Sanchez, P., van Staveren, D. R., & Alberto, R. (2007).
Structures of the b- and d-acid derivatives of vitamin B-12 and their complexes with M(CO)(3)](+) (M=Tc-99m, Re)
European Journal of Inorganic Chemistry, 2641–2647. https://doi.org/10.1002/ejic.200601195
Da Pieve, C., Medina-Molner, A., & Spingler, B. (2007).
Efficient routes for the synthesis of 1,4,7,10,13-pentaazacyclohexadecane-14,16-dione
Synthesis, 679–682. https://doi.org/10.1055/s-2007-965924
Kunz, P., Kurz, P., Spingler, B., & Alberto, R. (2007).
Tricarbonyltris(pyrazol-1-yl)methanesulfonato-kappa N-3,N `,N `’] rhenium(I) acetone solvate. Acta Crystallographica Section E: Crystallographic Communications, 63, M363–M364.
https://doi.org/10.1107/S1600536806055942
Ruiz-Sanchez, P., Mundwiler, S., Medina-Molner, A., Spingler, B., & Alberto, R. (2007).
Iodination of cisplatin adduct of Vitamin B-12 {B-12}-CN-{cis-PtCl(NH3)(2)}](+)
Journal of Organometallic Chemistry, 692, 1358–1362. https://doi.org/10.1016/j.jorganchem.2006.11.005
Agorastos, N., Borsig, L., Renard, A., Antoni, P., Viola, G., Spingler, B., Kurz, P., & Alberto, R. (2007).
Cell-specific and nuclear targeting with M(CO)(3)](+) (M=Tc-99m, Re)-based complexes conjugated to acridine orange and bombesin
Chemistry, 13, 3842–3852. https://doi.org/10.1002/chem.200700031
2006
Maria, L., Paulo, A., Santos, I. C., Santos, I., Kurz, P., Spingler, B., & Alberto, R. (2006).
Very small and soft scorpionates: Water stable technetium tricarbonyl complexes combining a bis-agostic (k(3)-H, H, S) binding motif with pendant and integrated bioactive molecules
Journal of the American Chemical Society, 128, 14590–14598. https://doi.org/10.1021/ja0644226
2005
Mundwiler, S., Spingler, B., Kurz, P., Kunze, S., & Alberto, R. (2005).
Cyanide-bridged vitamin B12-cisplatin conjugates.
Chemistry, 11, 4089–4095. https://doi.org/10.1002/chem.200500117
Mundwiler, S., Waibel, R., Spingler, B., Kunze, S., & Alberto, R. (2005).
Picolylamine-methylphosphonic acid esters as tridentate ligands for the labeling of alcohols with the fac-[M(CO)3]+ core (M = 99mTc, Re): synthesis and biodistribution of model compounds and of a 99mTc-labeled cobinamide.
Nuclear Medicine and Biology, 32, 473–484. https://doi.org/10.1016/j.nucmedbio.2005.04.007
Kurz, P., Rattat, D., Angst, D., Schmalle, H. W., Spingler, B., Alberto, R., Berke, H., & Beck, W. (2005).
The chemistry of the fac-[Re(CO)2(NO)]2+ fragment in aqueous solution.
Dalton Transactions, 4, 804–810. https://doi.org/10.1039/b417425a
Häfliger, P., Agorastos, N., Spingler, B., Georgiev, O., Viola, G., & Alberto, R. (2005).
Induction of DNA-double-strand breaks by auger electrons from 99mTc complexes with DNA-binding ligands.
Chembiochem, 6, 414–421. https://doi.org/10.1002/cbic.200400210
Dumas, C., Petrig, J., Frei, L., Spingler, B., & Schibli, R. (2005).
Functionalization of glucose at position C-3 for transition metal coordination: Organo-rhenium complexes with carbohydrate skeletons
Bioconjugate Chemistry, 16, 421–428. https://doi.org/10.1021/bc049744i
Schibli, R., Marti, N., Maurer, P., Spingler, B., Lehaire, M. L., Gramlich, V., & Barnes, C. L. (2005).
Syntheses and characterization of dicarbonyl-nitrosyl complexes of technetium(I) and rhenium(I) in aqueous media: Spectroscopic, structural, and DFT analyses
Inorganic Chemistry, 44, 683–690. https://doi.org/10.1021/ic049599k
Hafliger, P., Mundwiler, S., Ortner, K., Spingler, B., Alberto, R., Andocs, G., Balogh, L., & Bodo, K. (2005).
Structure, stability, and biodistribution of cationic M(CO)(3)](+) (M = Re, Tc-99, Tc-99m) complexes with tridentate amine ligands
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 35, 27–34. https://doi.org/10.1081/SIM-200047534
2004
Kunze, S., Zobi, F., Kurz, P., Spingler, B., & Alberto, R. (2004).
Vitamin B12 as a ligand for technetium and rhenium complexes.
Angewandte Chemie Internationale Edition, 43, 5025–5029. https://doi.org/10.1002/anie.200460923
van Staveren, D. R., Mundwiler, S., Hoffmanns, U., Pak, J. K., Spingler, B., Metzler-Nolte, N., & Alberto, R. (2004).
Conjugation of a novel histidine derivative to biomolecules and labelling with [99mTc(OH2)3(CO)3]+.
Organic & Biomolecular Chemistry, 2, 2593–2603. https://doi.org/10.1039/B405575F
Zobi, F., Blacque, O., Schmalle, H. W., Spingler, B., & Alberto, R. (2004).
Head-to-head (HH) and head-to-tail (HT) conformers of cis-bis guanine ligands bound to the [Re(CO)3]+ core.
Inorganic Chemistry, 43, 2087–2096. https://doi.org/10.1021/ic035012a
Masi, S., Top, S., Boubekeur, L., Jaouen, G., Mundwiler, S., Spingler, B., & Alberto, R. (2004).
Direct synthesis of tricarbonyl(cyclopentadienyl)rhenium and tricarbonyl(cyclopentadienyl)technetium units from ferrocenyl moieties - Preparation of 17 alpha-ethynylestradiol derivatives bearing a tricarbonyl(cyclopentadienyl)technetium group
European Journal of Inorganic Chemistry, 2013–2017. https://doi.org/10.1002/ejic.200300731
Kuzelka, J., Mukhopadhyay, S., Spingler, B., & Lippard, S. J. (2004).
Synthesis and characterization of Cu$_{2}$(I,I), Cu$_2$(I,II), and Cu$_2$(II,II), compounds supported by two phthalazine-based ligands: Influence of a hydrophobic pocket
Inorganic Chemistry, 43, 1751–1761. https://doi.org/10.1021/ic035009r
2003
Pak, J. K., Benny, P., Spingler, B., Ortner, K., & Alberto, R. (2003).
N(epsilon) functionalization of metal and organic protected L-histidine for a highly efficient, direct labeling of biomolecules with [Tc(OH2)3(CO)3]+.
Chemistry, 9, 2053–2061. https://doi.org/10.1002/chem.200204445
Zobi, F., Spingler, B., Fox, T., & Alberto, R. (2003).
Toward novel DNA binding metal complexes: structure and basic kinetic data of [M(9MeG)2(CH3OH)(CO)3]+(M = 99Tc, Re).
Inorganic Chemistry, 42, 2818–2820. https://doi.org/10.1021/ic030028m
Bernard, J., Ortner, K., Spingler, B., Pietzsch, H.-J., & Alberto, R. (2003).
Aqueous synthesis of derivatized cyclopentadienyl complexes of technetium and rhenium directed toward radiopharmaceutical application.
Inorganic Chemistry, 42, 1014–1022. https://doi.org/10.1021/ic0204575
Kuzelka, J., Mukhopadhyay, S., Spingler, B., & Lippard, S. J. (2003).
Modeling features of the non-heme diiron cores in O-2-activating enzymes through the synthesis, characterization, and oxidation of 1,8-naphthyridine-based complexes
Inorganic Chemistry, 42, 6447–6457. https://doi.org/10.1021/ic0345976
Boerzel, H., Koeckert, M., Bu, W. M., Spingler, B., & Lippard, S. J. (2003).
Zinc-bound thiolate-disulfide exchange: A strategy for inhibiting metallo-beta-lactamases
Inorganic Chemistry, 42, 1604–1615. https://doi.org/10.1021/ic025624f
2002
Bino, A., Ardon, M., Lee, D., Spingler, B., & Lippard, S. J. (2002).
Synthesis and structure of Fe13O4F24(OMe)(12)](5-): The first open-shelf Keggin ion
Journal of the American Chemical Society, 124, 4578–4579. https://doi.org/10.1021/ja025590a
Baumeister, J. M., Alberto, R., Ortner, K., Spingler, B., Schubiger, P. A., & Kaden, T. A. (2002).
Central vs. peripheral Ag(I) coordination in NS3-open chain and cage ligands
Journal of the Chemical Society, Dalton Transactions, 4143–4151. https://doi.org/10.1039/b205287c
2001
Mizoguchi, T. J., Kuzelka, J., Spingler, B., DuBois, J. L., Davydov, R. M., Hedman, B., Hodgson, K. O., & Lippard, S. J. (2001).
Synthesis and spectroscopic studies of non-heme diiron(III) species with a terminal hydroperoxide ligand: Models for hemerythrin
Inorganic Chemistry, 40, 4662–4673. https://doi.org/10.1021/ic010076b
Burdette, S. C., Walkup, G. K., Spingler, B., Tsien, R. Y., & Lippard, S. J. (2001).
Fluorescent sensors for Zn2+ based on a fluorescein platform: Synthesis, properties and intracellular distribution
Journal of the American Chemical Society, 123, 7831–7841. https://doi.org/10.1021/ja010059l
Pagination