Heinz Heimgartner received his Diploma in chemistry from the University of Zurich (1968) and completed his Ph.D. work under the guidance of H. Schmid (1972). Throughout his career, he has been associated with the Institute of Organic Chemistry. He became Privatdozent in 1980, Titularprofessor in 1987, and in 1995 he was appointed Associate Professor. Since 2006 he is Emeritus Professor. He was awarded the Werner Prize and Medal of the Swiss Chemical Society in 1978, the Medal "In Service of Science and Society" of the University of Lodz in 2001, the Honorary Membership of the Polish Chemical Society in 2002, the Kametani Award in 2005, the Team Prize 2007 of the Polish Ministry of Science and Higher Education, the Doctor Honoris Causa of the University of Lodz in 2009, and the Professor Honoris Causa of the State University St. Petersburg in 2010.
Research Interests:Research activities range from photochemistry and mechanisms of organic reactions to the preparation of heterocyclic compounds and the synthesis and conformation of peptides. The group has developed general methods for introduction of a,a-disubstituted glycines into linear and cyclic peptides, enabling synthesis of model peptides with restricted conformations, and possibility of naturally occurring membrane modifying peptaibols. A convenient lactone formation via direct amide cyclization enables cyclic depsipeptides with potential ionophoric activities to be synthesized. Recently, new approaches to selenium containing heterocycles overcomes instability and toxicity problems.
Synthese von Heterocyclen durch Ringerweiterung von 2H-Azirinen
H. Heimgartner, Wiss. Z. Karl-Marx-Univ. Leipzig, Math.-Naturwiss. R. 1983,
2-Thiazolin-5-thiones, a New Type of Sulfur Heterocycle; Synthesis and
H. Heimgartner, Croatica Chem. Acta 1986, 59, 237-265.
The Application of 3-Amino-2H-azirines as Amino Acid Equivalents
H. Heimgartner, Israel J. Chem. 1986, 27, 3-15.
3-Amino-2H-azirines, Synthons for α,α-Disubstituted α-Amino Acids in
Heterocycle and Peptide Synthesis
H. Heimgartner, Angew. Chem., Int. Ed. 1991, 30, 238-265.
Addition Reactions with 1,3-Thiazole-5(4H)-thiones; Synthesis of Spirocyclic
and Fused Bicyclic Sulfur Heterocycles
H. Heimgartner, Phosphorus, Sulfur and Silicon 1991, 58, 281-293.
1,3-Oxazol-5(4H)-ones as Intermediates in the Formation of Macrolides,
Cyclodepsipeptides and Cyclopeptides
H. Heimgartner, F. S. Arnhold, S. P. Fritschi, K. N. Koch, J. E. F. Magirius, A.
Linden, J. Heterocycl. Chem. 1999, 36, 1539-1547.
Regio- and Stereoselective Formation of 1,3-Oxathiolanes by Reactions of
Thiocarbonyl Compounds with Oxiranes
H. Heimgartner, C. Fu, M. Blagoev, A. Linden, Phosphorus, Sulfur, and Silicon
2005, 180, 1309-1313.
Isoselenocyanates as Building Blocks for Selenium-Containing Heterocycles
H. Heimgartner, Y. Zhou, P. K. Atanassov, G. L. Sommen, Phosphorus, Sulfur,
and Silicon and the Related Elements 2008, 183, 840-855.